Pulmonary amyloidosis as the presenting finding in a patient with multiple myeloma

被引：1

作者：

Kronen, Ryan ^{[1
]}

Ziehr, David R. ^{[2
]}

Kane, Ashley E. D. ^{[3
]}

VanderLaan, Paul A. ^{[4
]}

Kholdani, Cyrus A. ^{[5
]}

Hallowell, Robert W. ^{[2
]}

机构：

[1] Univ Washington, Dept Med, 1959 NE Pacific St, Seattle, WA 98195 USA

[2] Massachusetts Gen Hosp, Dept Med, Div Pulm & Crit Care Med, Boston, MA 02114 USA

[3] Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA

[4] Beth Israel Deaconess Med Ctr, Dept Pathol, 330 Brookline Ave, Boston, MA 02215 USA

[5] Beth Israel Deaconess Med Ctr, Dept Med, Div Pulm Crit Care & Sleep Med, Boston, MA 02215 USA

来源：

RESPIRATORY MEDICINE CASE REPORTS | 2022年 / 37卷

关键词：

Multiple myeloma; Pulmonary amyloidosis; Light chain (AL) amyloidosis; Case report; ARTERIAL-HYPERTENSION; DEPOSITION;

D O I：

10.1016/j.rmcr.2022.101626

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

We present the case of a 58-year-old man who presented with dyspnea, cough, and weight loss and was ultimately diagnosed with pulmonary amyloidosis and multiple myeloma. Diagnosis was achieved with a lung biopsy which showed AL amyloid deposits involving the interstitium, vessels, and airway. He was treated with cyclophosphamide, bortezomib, and dexamethasone but died prior to completing treatment. His case is unique for the amyloid deposition found in all three lung compartments with clear pathophysiologic manifestations of each compartment, and the rapid disease progression that led to respiratory failure and death.

引用

页数：4

共 17 条

[1] Pulmonary light chain deposition disease - Report of five cases and review of the literature [J].