Catalytic C-H functionalization driven by CO as a stoichiornetric reductant: Application to carbazole synthesis

被引：134
作者：
Smitrovich, JH [1 ]
Davies, IW [1 ]
机构：
[1] Merck & Co Inc, Dept Proc Res, Rahway, NJ 07065 USA
来源：
ORGANIC LETTERS | 2004年 / 6卷 / 04期
关键词：
D O I：
10.1021/ol036294l
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A palladium-catalyzed regioselective C-H bond functionalization driven by CO as the stoichiometric reductant is described. Nitrogen heterocycles, e.g., carbazoles, are accessible in good to excellent yields with use of palladium acetate and 70 psig of carbon monoxide at 140 degreesC.
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页码：533 / 535
页数：3
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