Selective internal radiation therapy by yttrium-90 microspheres for hepatocellular carcinoma after renal transplantation

被引：1

作者：

Szeto, CC ^{[1
]}

Wong, TYH ^{[1
]}

Leung, CB ^{[1
]}

Leung, TWT ^{[1
]}

Wang, AYM ^{[1
]}

Lui, SF ^{[1
]}

Li, PKT ^{[1
]}

机构：

[1] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Med & Therapeut, Shatin, Hong Kong, Peoples R China

来源：

CLINICAL TRANSPLANTATION | 2001年 / 15卷 / 04期

关键词：

hepatocellular carcinoma; kidney transplant; radiotherapy;

D O I：

10.1034/j.1399-0012.2001.150411.x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

We report a HBsA-positive patient who developed hepatocellular carcinoma (HCC) 7 years after cadaveric kidney transplantation. The tumor was unresectable because of coexisting cirrhosis. Selective internal radiation (SIR) therapy, a novel therapy with the technique recently perfected, was used. Yttrium-90 microspheres were given via an angiographic catheter under fluoroscopy guidance. Serum alpha-fetal protein (AFP) was normalized within 2 wk. A follow-up abdominal CT scan revealed significant necrosis of the tumor and compensatory hypertrophy of non-diseased liver. The treatment was well tolerated except for transient liver function deterioration. The patient enjoyed 15 months of symptom-free survival before she died of liver failure. Practical aspects and potential applications of SIR therapy in this group of patients are discussed.

引用

页码：284 / 288

页数：5