Benefits of non-surgical periodontal treatment in patients with type 2 diabetes mellitus and chronic periodontitis: A randomized controlled trial

被引:94
作者
Mauri-Obradors, Elisabet [1 ]
Merlos, Alexandra [2 ]
Estrugo-Devesa, Albert [1 ]
Jane-Salas, Enric [1 ,3 ,4 ,5 ]
Lopez-Lopez, Jose [1 ,3 ,4 ,5 ]
Vinas, Miguel [2 ]
机构
[1] Univ Barcelona, Dept Dent, Sch Dent, Barcelona, Spain
[2] IDIBELL Univ Barcelona, Dept Pathol & Expt Therapeut, Sch Med, Barcelona, Spain
[3] IDIBELL, Oral Med Unit, Dept Dent, Fac Med & Hlth Sci,Dent Sch, Barcelona, Spain
[4] Univ Barcelona, Dent Hosp, Barcelona, Spain
[5] IDIBELL, Hlth & Masticatory Syst Grp, Bellvitge Biomed Res Inst, Barcelona, Spain
关键词
glycosylated haemoglobin; PCR; periodontal disease; scaling and root planing; type 2 diabetes mellitus; GLYCEMIC CONTROL; METABOLIC-CONTROL; THERAPY; DISEASE; COMPLICATIONS; TAQMAN; HBA1C; CARE;
D O I
10.1111/jcpe.12858
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
BackgroundPeriodontitis and diabetes are highly prevalent conditions whose association has long been recognized. ObjectiveTo evaluate the effect of non-surgical periodontal treatment on serum HbA1c (haemoglobin A1c or glycated haemoglobin) levels in patients with type 2 diabetes. Research Design and MethodsThis was a 6-month, single-masked, randomized clinical trial based on 90 patients (HbA1c: 7.7% (61mmol/mol)1.13%) who were randomly assigned to either the treatment group (oral hygiene instructions+scaling and root planing using ultrasound and Gracey curettes) or the control group (oral hygiene instructions+supragingival removal of plaque and calculus using ultrasound). Pocket depth, gingival index, and plaque index were assessed at baseline and after 3 and 6months together with determinations of fasting plasma glucose, HbA1c, and bacterial counts. ResultsTreatment significantly improved the periodontal and metabolic parameters (p<.05), whereas in the control group no improvement was observed. These results were consistent with the bacteriological results in most but not all cases. ConclusionNon-surgical periodontal treatment resulted in a better glycaemic status of type 2 diabetes patients and demonstrated the importance of oral health in their general health.
引用
收藏
页码:345 / 353
页数:9
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