Beneficial Effects of Kimchi, a Korean Fermented Vegetable Food, on Pathophysiological Factors Related to Atherosclerosis

被引:22
作者
Kim, Hyun Ju [1 ]
Noh, Jeong Sook [2 ]
Song, Yeong Ok [3 ]
机构
[1] World Inst Kimchi, Div Res & Dev, Ind Technol Res Grp, Gwangju, South Korea
[2] Tongmyong Univ, Dept Food Sci & Nutr, Busan, South Korea
[3] Pusan Natl Univ, Kimchi Res Inst, Dept Food Sci & Nutr, 2 Busandaehak Ro,63beon Gil, Busan 46241, South Korea
关键词
<bold>atherosclerosis</bold>; <bold>hypercholesterolemia</bold>; <bold>kimchi</bold>; <bold>LDL oxidation</bold>; <bold>3-(4-Hydroxyl-3; </bold><bold>5-dimethoxyphenyl)propionic acid</bold>; ENDOPLASMIC-RETICULUM STRESS; UNFOLDED PROTEIN RESPONSE; LOW-DENSITY-LIPOPROTEIN; FOAM CELL-FORMATION; ACTIVE PRINCIPLE; RED-PEPPER; 3-(4'-HYDROXYL-3'; 5'-DIMETHOXYPHENYL)PROPIONIC ACID; CABBAGE KIMCHI; OXIDIZED LDL; HIGH-FAT;
D O I
10.1089/jmf.2017.3946
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Atherosclerosis is a progressive disease that is characterized by accumulation of lipids and fibrous elements in large arteries. Its etiology is involved with pathophysiological factors such as lipoprotein oxidation, inflammation, and dyslipidemia. Kimchi is a Korean fermented vegetable side dish made with vegetables and kimchi condiments. To date, numerous in vitro, in vivo, and human studies have cited the health benefits of kimchi. 3-(4-Hydroxyl-3,5-dimethoxyphenyl)propionic acid is one of the active compounds of kimchi, and its antioxidant and anti-atherosclerosclerotic effects have been reported. This review presents the laboratory and clinical evidence of the anti-atherosclerotic effects of kimchi based on its lipid-lowering, antioxidant, and anti-inflammatory activities.
引用
收藏
页码:127 / 135
页数:9
相关论文
共 88 条
[1]  
[Anonymous], 2017, J AM HEART ASS
[2]  
[Anonymous], 1998, J KOREAN SOC FOOD SC
[3]  
[Anonymous], 2001, J KOREAN SOC FOOD SC
[4]  
Austin RC, 2009, ANTIOXID REDOX SIGN, V11, P2279, DOI [10.1089/ars.2009.2686, 10.1089/ARS.2009.2686]
[5]   Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation [J].
Bailey, Keith A. ;
Haj, Fawaz G. ;
Simon, Scott I. ;
Passerini, Anthony G. .
SCIENTIFIC REPORTS, 2017, 7
[6]   Cigarette Smoke Amplifies Inflammatory Response and Atherosclerosis Progression Through Activation of the H1R-TLR2/4-COX2 Axis [J].
Barua, Rajat S. ;
Sharma, Mukut ;
Dileepan, Kottarappat N. .
FRONTIERS IN IMMUNOLOGY, 2015, 6
[7]  
공연희, 2007, [Journal of the Korean Society of Food Science and Nutrition, 한국식품영양과학회지], V36, P1529
[8]   BIOCHEMICAL, MICROBIOLOGICAL, AND NUTRITIONAL ASPECTS OF KIMCHI (KOREAN FERMENTED VEGETABLE PRODUCTS) [J].
CHEIGH, HS ;
PARK, KY .
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 1994, 34 (02) :175-203
[9]   Autophagy Induction by Capsaicin in Malignant Human Breast Cells Is Modulated by p38 and Extracellular Signal-Regulated Mitogen-Activated Protein Kinases and Retards Cell Death by Suppressing Endoplasmic Reticulum Stress-Mediated Apoptosis [J].
Choi, Cheol-Hee ;
Jung, Yong-Keun ;
Oh, Seon-Hee .
MOLECULAR PHARMACOLOGY, 2010, 78 (01) :114-125
[10]   Kimchi, a Fermented Vegetable, Improves Serum Lipid Profiles in Healthy Young Adults: Randomized Clinical Trial [J].
Choi, In Hwa ;
Noh, Jeong Sook ;
Han, Ji-Sook ;
Kim, Hyun Ju ;
Han, Eung-Soo ;
Song, Yeong Ok .
JOURNAL OF MEDICINAL FOOD, 2013, 16 (03) :223-229