Expanding the Benefits of Implantable Cardioverter-Defibrillator Therapy: "Is Less More"?

被引:3
作者
Jackson, Larry R., II [2 ]
Daubert, James P. [1 ]
Thomas, Kevin L. [1 ]
机构
[1] Duke Univ, Sch Med, Duke Clin Res Inst, Durham, NC USA
[2] Duke Univ, Sch Med, Dept Med, Electrophysiol Sect,Cardiol Div, Durham, NC 27706 USA
关键词
RAPID VENTRICULAR-TACHYCARDIA; HEART-FAILURE; SHOCKS; SURVIVAL; TRIAL; PREVENTION; PREDICTORS; MORTALITY; DISEASE/; PATIENT;
D O I
10.1016/j.pcad.2011.11.002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Implantable cardioverter-defibrillator (ICD) therapy improves survival in patients with significant left ventricular systolic dysfunction. Although this lifesaving therapy has many benefits, inappropriate ICD shocks may increase morbidity and mortality. With rates of inappropriate therapy quoted as high as 35% at 3 years after device implantation, numerous strategies have been evaluated to decrease the overall incidence of inappropriate therapy. Changes in programming algorithms, which allow for longer detection windows for rhythm analysis, extended the use of antitachycardia pacing, and improved supraventricular tachycardia discriminators, hold promise for decreasing inappropriate ICD therapy. In this review, we discuss the data summarizing the adverse effects of ICD shocks on outcomes, clinical trial-based programming algorithms to decrease inappropriate shocks, and the expanded role of antitachycardia pacing in ventricular arrhythmia management. (Prog Cardiovasc Dis 2012;54:372-378) (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码:372 / 378
页数:7
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