Subgroup analyses in randomized clinical trials: value and limitations. Review #3 on important aspects of randomized clinical trials in cardiovascular pharmacotherapy

被引：6

作者：

Drexel, Heinz ^{[1
,2
,3
,4
]}

Pocock, Stuart J. ^{[5
]}

Lewis, Basil S. ^{[6
,7
]}

Saely, Christoph H. ^{[1
,3
,8
]}

Kaski, Juan Carlos ^{[9
]}

Rosano, Giuseppe M. C. ^{[10
]}

Tautermann, Gerda ^{[1
,3
,8
]}

Huber, Kurt ^{[11
,12
]}

Dopheide, Joern F. ^{[1
,13
]}

Mader, Arthur ^{[1
,3
,8
]}

Niessner, Alexander ^{[14
]}

Savarese, Gianluigi ^{[15
]}

Schmidt, Thomas A. ^{[16
]}

Semb, Anne Grete ^{[17
]}

Tamargo, Juan ^{[18
]}

Wassmann, Sven ^{[19
,20
]}

Clodi, Martin ^{[21
]}

Kjeldsen, Keld Per ^{[22
,23
]}

Agewall, Stefan ^{[24
,25
]}

机构：

[1] Vorarlberg Inst Vasc Invest & Treatment VIVIT, Feldkirch, Austria

[2] Cty Hosp Bregenz, Dept Med, Bregenz, Austria

[3] Private Univ Principal Liechtenstein, Triesen, Liechtenstein

[4] Drexel Univ, Coll Med, Philadelphia, PA 19104 USA

[5] London Sch Hyg & Trop Med, Dept Med Stat, London, England

[6] Lady Davis Carmel Med Ctr, Cardiovasc Clin Res Inst, Haifa, Israel

[7] Technion Israel Inst Technol, Ruth & Bruce Rappaport Sch Med, Haifa, Israel

[8] Acad Teaching Hosp Feldkirch, Dept Med 1, Feldkirch, Austria

[9] St Georges Univ London, Mol & Clin Sci Res Inst, London, England

[10] IRCCS San Raffaele Hosp, Dept Med Sci, Rome, Italy

[11] Wilhelminen Hosp, Med Dept Cardiol & Intens Care Med 3, Vienna, Austria

[12] Sigmund Freud Univ, Med Sch, Dept Cardiol, Vienna, Austria

[13] Cantonal Hosp Graubunden, Dept Angiol, Chur, Switzerland

[14] Med Univ Vienna, Dept Internal Med 2, Vienna, Austria

[15] Karolinska Univ Hosp, Dept Med, Cardiol Unit, Stockholm, Sweden

[16] North Zealand Univ Hosp, Dept Emergency Med, Hillerod, Denmark

[17] Diakonhjemmet Hosp, Div Rheumatol & Res, Prevent Cardio Rheuma Clin, Oslo, Norway

[18] Univ Complutense, Sch Med, Dept Pharmacol & Toxicol, CIBERCV, Madrid, Spain

[19] Cardiol Pasing, Munich, Germany

[20] Univ Saarland, Med Fac, Clin Med, Homburg, Germany

[21] St John God Hosp Linz, Dept Med, Linz, Austria

[22] Copenhagen Univ Hosp Amager Hvidovre, Dept Cardiol, Copenhagen, Denmark

[23] Aalborg Univ, Fac Med, Dept Hlth Sci & Technol, Aalborg, Denmark

[24] Oslo Univ Hosp, Dept Cardiol, Oslo, Norway

[25] Univ Oslo, Inst Clin Sci, Sosterhjemmet, Oslo, Norway

来源：

EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY | 2022年 / 8卷 / 03期

关键词：

Randomized clinical trials; Subgroup analyses; Cardiovascular pharmacotherapy; OUTCOMES; APIXABAN; WARFARIN; INSIGHTS; THERAPY;

D O I：

10.1093/ehjcvp/pvab048

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：302 / 310

页数：9

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