Curvature factor and membrane solubilization, with particular reference to membrane rafts

被引:11
|
作者
Mrowczynska, Lucyna [2 ]
Salzer, Ulrich [3 ]
Iglic, Ales [4 ]
Hagerstrand, Henry [1 ]
机构
[1] Abo Akad Univ, Dept Biosci, FIN-20520 Turku, Finland
[2] Adam Mickiewicz Univ, Dept Cell Biol, PL-61614 Poznan, Poland
[3] Med Univ Vienna, Max F Perutz Labs, A-1030 Vienna, Austria
[4] Fac Elect Engn, Biophys Lab, SI-1000 Ljubljana, Slovenia
关键词
detergent-resistant membrane; membrane curvature; raft; solubilization; Triton X-100; DETERGENT-RESISTANT MEMBRANES; ERYTHROCYTES FOLLOWING TREATMENT; LIPID RAFTS; PLASMA-MEMBRANE; CELL-MEMBRANES; TRITON X-100; PHYSIOLOGICAL TEMPERATURE; SHAPE TRANSFORMATIONS; BIOLOGICAL-MEMBRANES; PROTEIN-COMPOSITION;
D O I
10.1042/CBI20100786
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The composition of membrane rafts (cholesterol/sphingolipid-rich domains) cannot be fully deduced from the analysis of a detergent-resistant membrane fraction after solubilization in Triton X-100 at 4 degrees C. It is hypothesized that the membrane curvature-dependent lateral distribution of membrane components affects their solubilization. The stomatocytogenic, Triton X-100, cannot effectively solubilize membrane components, especially with regard to the outward membrane curvature.
引用
收藏
页码:991 / 995
页数:5
相关论文
共 50 条
  • [41] Membrane curvature in flaviviruses
    Zhang, Wei
    Kaufmann, Baerbel
    Chipman, Paul R.
    Kuhn, Richard J.
    Rossmann, Michael G.
    JOURNAL OF STRUCTURAL BIOLOGY, 2013, 183 (01) : 86 - 94
  • [42] Sensing membrane curvature
    Holthuis, JCM
    Burger, KNJ
    DEVELOPMENTAL CELL, 2003, 5 (06) : 821 - 822
  • [43] Heterogeneity of neuronal plasma membrane rafts
    Mosevitsky, MI
    Malikova, SL
    JOURNAL OF NEUROCHEMISTRY, 2001, 78 : 20 - 20
  • [44] Membrane curvature at a glance
    McMahon, Harvey T.
    Boucrot, Emmanuel
    JOURNAL OF CELL SCIENCE, 2015, 128 (06) : 1065 - 1070
  • [45] Cholesterol and other membrane active sterols: from membrane evolution to "rafts"
    Barenholz, Y
    PROGRESS IN LIPID RESEARCH, 2002, 41 (01) : 1 - 5
  • [46] Gangliosides and Lysolipids Regulate the Size of Membrane Rafts Depending on the Membrane Composition
    Lyushnyak, Anna S.
    Krasnobaev, Vladimir D.
    Galimzyanov, Timur R.
    Akimov, Sergey A.
    Batishchev, Oleg V.
    BIOPHYSICAL JOURNAL, 2018, 114 (03) : 271A - 271A
  • [47] Polyphosphoinositides Are Enriched in Plant Membrane Rafts and Form Microdomains in the Plasma Membrane
    Furt, Fabienne
    Koenig, Sabine
    Bessoule, Jean-Jacques
    Sargueil, Francoise
    Zallot, Remi
    Stanislas, Thomas
    Noirot, Elodie
    Lherminier, Jeanine
    Simon-Plas, Francoise
    Heilmann, Ingo
    Mongrand, Sebastien
    PLANT PHYSIOLOGY, 2010, 152 (04) : 2173 - 2187
  • [48] Titration calorimetry of surfactant-membrane partitioning and membrane solubilization
    Heerklotz, H
    Seelig, J
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2000, 1508 (1-2): : 69 - 85
  • [49] MEMBRANE-ALTERATIONS IN HEALTH AND DISEASE WITH PARTICULAR REFERENCE TO IMMUNE FUNCTION AND CANCER
    RAY, PK
    PRASAD, AK
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 1989, 91 (1-2) : 13 - 21
  • [50] TRANSITION RADIATION FROM AN ANISOTROPIC DIELECTRIC LAYER WITH PARTICULAR REFERENCE TO BIOLOGICAL MEMBRANE
    LAM, J
    JOURNAL OF PHYSICS PART A GENERAL, 1969, 2 (05): : 529 - &