Alternative to Rituximab Therapy for a Patient with Ankylosing Spondylitis Who Was Unable to Continue Anti-TNF Therapy

被引：0

作者：

Katsuyama, Eri ^{[1
]}

Wakabayashi, Hiroshi ^{[2
]}

Sada, Ken-ei ^{[1
]}

Hiramatsu, Sumie ^{[1
]}

Miyawaki, Yoshia ^{[1
]}

Morishita, Michiko ^{[1
]}

Ohashi, Keiji ^{[1
]}

Watanabe, Haruki ^{[1
]}

Katsuyama, Takayuki ^{[1
]}

Zeggar, Sonia ^{[1
]}

Narazaki, Mariko ^{[1
]}

Tatebe, Noriko ^{[1
]}

Watanabe, Katsue S. ^{[1
]}

Kawabata, Tomoko ^{[1
]}

Wada, Jun ^{[1
]}

机构：

[1] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Nephrol Rheumatol Endocrinol & Metab, Okayama 7008558, Japan

[2] Okayama Municipal Hosp, Okayama 7000962, Japan

来源：

ACTA MEDICA OKAYAMA | 2017年 / 71卷 / 05期

关键词：

ankylosing spondylitis; rituximab; treatment; OPEN-LABEL; INFLIXIMAB; TRIAL; INFLAMMATION; ABATACEPT;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We herein present a case of a 38-year-old man who had bamboo spine and severe sacroiliitis and who was diagnosed with ankylosing spondylitis (AS). Infliximab (IFX) markedly improved the axial symptom but was discontinued due to the side effect of peripheral neuropathy. Switching from IFX to etanercept worsened the side effect. Rituximab (RTX) administration elicited a good response without side effects. RTX might be a suitable option for AS therapy when TNF inhibitors are difficult to use.

引用

页码：445 / 448

页数：4

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