Visualization of sequence and structural features of genomes and chromosome fragments. Application to CpG islands, Alu sequences and whole genomes

被引：0

作者：

Subirana, Juan A. ^{[1
]}

Anokian, Ezequiel ^{[1
]}

机构：

[1] Univ Politecn Cataluna, Dept Engn Quim, E-08028 Barcelona, Spain

来源：

GENE | 2011年 / 473卷 / 02期

关键词：

DNA structure; Non-coding DNA; DNA repeats; Genome sequence analysis; DNA;

D O I：

10.1016/j.gene.2010.11.008

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A very simple new program is presented (G-SQUARES). It is useful in order to visualize the composition and basic structural features of whole genomes and selected chromosome regions. The frequency of all dimer and tetramer sequences is reported. Overall structural features are calculated, such as the tendency for alternation. A direct visual comparison among different sequences is easily available. Furthermore, the features which are visualized indicate further studies which should be carried out. Examples are presented on Alu sequences, CpG islands, whole eukaryotic and bacterial genomes. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：76 / 81

页数：6