Generic signals and specific outcomes:: Signaling through Ca2+, calcineurin, and NF-AT

被引:640
作者
Crabtree, GR [1 ]
机构
[1] Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94062 USA
[2] Stanford Univ, Sch Med, Dept Dev Biol, Stanford, CA 94062 USA
关键词
D O I
10.1016/S0092-8674(00)80571-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:611 / 614
页数:4
相关论文
共 25 条
[1]   Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells [J].
Abbott, KL ;
Friday, BB ;
Thaloor, D ;
Murphy, TJ ;
Pavlath, GK .
MOLECULAR BIOLOGY OF THE CELL, 1998, 9 (10) :2905-2916
[2]   Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3 [J].
Beals, CR ;
Sheridan, CM ;
Turck, CW ;
Gardner, P ;
Crabtree, GR .
SCIENCE, 1997, 275 (5308) :1930-1933
[3]   Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction [J].
Beals, CR ;
Clipstone, NA ;
Ho, SN ;
Crabtree, GR .
GENES & DEVELOPMENT, 1997, 11 (07) :824-834
[4]   Calcium - a life and death signal [J].
Berridge, MJ ;
Bootman, MD ;
Lipp, P .
NATURE, 1998, 395 (6703) :645-648
[5]   Structure of the DNA binding domains from NFAT, Fos and Jun bound specifically to DNA [J].
Chen, L ;
Glover, JNM ;
Hogan, PG ;
Rao, A ;
Harrison, SC .
NATURE, 1998, 392 (6671) :42-48
[6]   A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type [J].
Chin, ER ;
Olson, EN ;
Richardson, JA ;
Yano, Q ;
Humphries, C ;
Shelton, JM ;
Wu, H ;
Zhu, WG ;
Bassel-Duby, R ;
Williams, RS .
GENES & DEVELOPMENT, 1998, 12 (16) :2499-2509
[7]   Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway [J].
Chow, CW ;
Rincon, M ;
Cavanagh, J ;
Dickens, M ;
Davis, RJ .
SCIENCE, 1997, 278 (5343) :1638-1641
[8]   NUCLEAR-ASSOCIATION OF A T-CELL TRANSCRIPTION FACTOR BLOCKED BY FK-506 AND CYCLOSPORINE-A [J].
FLANAGAN, WM ;
CORTHESY, B ;
BRAM, RJ ;
CRABTREE, GR .
NATURE, 1991, 352 (6338) :803-807
[9]  
GOLDSMITH MA, 1989, J BIOL CHEM, V264, P17190
[10]   EARLY SIGNAL TRANSDUCTION BY THE ANTIGEN RECEPTOR WITHOUT COMMITMENT TO T-CELL ACTIVATION [J].
GOLDSMITH, MA ;
WEISS, A .
SCIENCE, 1988, 240 (4855) :1029-1031