Cytokines, tumour-cell death and immunogenicity: A question of choice

被引：178
作者：
Musiani, P
Modesti, A
Giovarelli, M
Cavallo, F
Colombo, MP
Lollini, PL
Forni, G
机构：
[1] UNIV TORINO,DIPARTIMENTO SCI CLINICHE & BIOL,TURIN,ITALY
[2] UNIV TORINO,CNR,CIOS,TURIN,ITALY
[3] UNIV BOLOGNA,IST CANCEROL,BOLOGNA,ITALY
[4] IST NAZL TUMORI,I-20133 MILAN,ITALY
来源：
IMMUNOLOGY TODAY | 1997年 / 18卷 / 01期
关键词：
D O I：
10.1016/S0167-5699(97)80012-6
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
How do cytokines released by engineered tumour cells provoke tumour rejection and an immune memory? Is vaccination with tumour cells that have been engineered to secrete cytokines a viable therapeutic perspective? Pier Musiani and colleagues have sought an answer to these questions by transfecting the same tumour with the genes of various cytokines and elucidating the features of the reactions elicited.
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页码：32 / 36
页数：5
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