Stem-cell homeostasis and growth dynamics can be uncoupled in the Arabidopsis shoot apex

被引：193

作者：

Reddy, GV ^{[1
]}

Meyerowitz, EM ^{[1
]}

机构：

[1] CALTECH, Div Biol, Pasadena, CA 91125 USA

来源：

SCIENCE | 2005年 / 310卷 / 5748期

关键词：

D O I：

10.1126/science.1116261

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The shoot apical meristem (SAM) is a collection of stem cells that resides at the tip of each shoot and provides the cells of the shoot. It is divided into functional regions. The central zone (CZ) at the tip of the meristem is the domain of expression of the CLAVATA3 (CLV3) gene, encoding a putative ligand for a transmembrane receptor kinase, CLAVATA1, active in cells of the rib meristem (RM), located just below the CZ. We show here that CLV3 restricts its own domain of expression (the CZ) by preventing differentiation of peripheral zone cells (PZ), which surround the CZ, into CZ Celts and restricts overall SAM size by a separate, tong-range effect on cell division rate.

引用

页码：663 / 667

页数：5

共 15 条

[1] Dependence of stem cell fate in Arabidopsis an a feedback loop regulated by CLV3 activity [J].