How to use statins in patients with chronic liver disease

被引：33
作者：
Russo, MW [1 ]
Jacobson, IM [1 ]
机构：
[1] Weill Cornell Med Coll, Div Gastroenterol & Hepatol, Ctr Study Hepatitis C, New York, NY USA
来源：
CLEVELAND CLINIC JOURNAL OF MEDICINE | 2004年 / 71卷 / 01期
关键词：
D O I：
10.3949/ccjm.71.1.58
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Clinicians may be concerned about prescribing statins to patients with chronic liver disease, but there is little evidence to suggest that drug-induced liver injury from statins is increased in these patients. Thus, we should prescribe statins for the same indications in patients with chronic liver disease as in patients without, but with closer monitoring. However, patients with acute liver disease (acute viral hepatitis, alcoholic hepatitis) should not take statins until they have recovered.
引用
收藏
页码：58 / 62
页数：5
相关论文
共 17 条
  • [11] Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes - The MIRACL study: A randomized controlled trial
    Schwartz, GG
    Olsson, AG
    Ezekowitz, MD
    Ganz, P
    Oliver, MF
    Waters, D
    Zeiher, A
    Chaitman, BR
    Leslie, S
    Stern, T
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (13): : 1711 - 1718
  • [12] Fluvastatin for prevention of cardiac events following successful first percutaneous coronary intervention - A randomized controlled trial
    Serruys, PWJC
    de Feyter, P
    Macaya, C
    Kokott, N
    Puel, J
    Vrolix, M
    Branzi, A
    Bertolami, MC
    Jackson, G
    Strauss, B
    Meier, B
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 287 (24): : 3215 - 3222
  • [13] Pharmacokinetics and pharmacodynamics of rosuvastatin in subjects with hepatic impairment
    Simonson, SG
    Martin, PD
    Mitchell, P
    Schneck, DW
    Lasseter, KC
    Warwick, MJ
    [J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2003, 58 (10) : 669 - 675
  • [14] The liver and lovastatin
    Tolman, KG
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 2002, 89 (12) : 1374 - 1380
  • [15] Drug administration in chronic liver disease
    Westphal, JF
    Brogard, JM
    [J]. DRUG SAFETY, 1997, 17 (01) : 47 - 73
  • [16] Wooltorton E, 2001, CAN MED ASSOC J, V165, P632
  • [17] Short-term effects of statin therapy in patients with hyperlipoproteinemia after liver transplantation: results of a randomized cross-over trial
    Zachoval, R
    Gerbes, AL
    Schwandt, P
    Parhofer, KG
    [J]. JOURNAL OF HEPATOLOGY, 2001, 35 (01) : 86 - 91
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