Nanoceria as antioxidant: Synthesis and biomedical applications

被引：300

作者：

Karakoti, A. S. ^{[1
]}

Monteiro-Riviere, N. A. ^{[2
,3
]}

Aggarwal, R. ^{[2
]}

Davis, J. P. ^{[4
]}

Narayan, R. J. ^{[2
]}

Self, W. T. ^{[5
]}

McGinnis, J. ^{[6
]}

Seal, S. ^{[1
,7
]}

机构：

[1] Univ Cent Florida, Surface Engn & Nanotechnol Facil, Adv Mat Proc & Anal Ctr, Dept Mech Mat & Aerosp Engn, Orlando, FL 32816 USA

[2] Univ N Carolina, Joint Dept Biomed Engn, Raleigh, NC USA

[3] N Carolina State Univ, Ctr Chem Toxicol Res & Pharmacokinet, Raleigh, NC 27695 USA

[4] N Carolina State Univ, USDA ARS Market Qual & Handling Res Unit, Deot Food Bioproc & Nutr Sci, Raleigh, NC 27695 USA

[5] Univ Cent Florida, Dept Mol Biol & Microbiol, Burnett Coll Biomed Sci, Orlando, FL 32816 USA

[6] Univ Oklahoma, Dept Ophthalmol, Dean A McGee Eye Inst, Oklahoma City, OK USA

[7] Univ Cent Florida, Nanosci & Technol Ctr, Orlando, FL 32816 USA

来源：

JOM | 2008年 / 60卷 / 03期

关键词：

D O I：

10.1007/s11837-008-0029-8

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The therapeutic application of nanomaterials has been a focus of numerous studies in the past decade. Due to its unique redox properties, cerium oxide (ceria) is finding widespread use in the treatment of medical disorders caused by the reactive oxygen intermediates (ROI). The radical-scavenging role of ceria nanoparticles (nanoceria) have been established, as well as the autocatalytic ability of nanoceria to regenerate under various environmental conditions. The synthesis of nanoceria in biocompatible media has also been reported along with cell viability in order to determine the potential use of nanoceria in biomedical applications.

引用

页码：33 / 37

页数：5

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