Design of Natural Food Antioxidant Ingredients through a Chemometric Approach

被引：15

作者：

Mendiola, Jose A. ^{[1
]}

Martin-Alvarez, Pedro J. ^{[1
]}

Javier Senorans, F. ^{[2
]}

Reglero, Guillermo ^{[2
]}

Capodicasa, Alessandro ^{[3
]}

Nazzaro, Filomena ^{[4
]}

Sada, Alfonso ^{[4
]}

Cifuentes, Alejandro ^{[1
]}

Ibanez, Elena ^{[1
]}

机构：

[1] CSIC, Inst Fermentac Ind, E-28006 Madrid, Spain

[2] Univ Autonoma Madrid, CSIC, Unidad Asociada, Secc Dept Ciencias Alimentac, E-28049 Madrid, Spain

[3] Bioma Agro Ecol CO, Quartino, Switzerland

[4] CNR, ISA, Avellino, Italy

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2010年 / 58卷 / 02期

关键词：

Antioxidant activity; simplex centroid mixture design; polyphenols; vitamins; MLR; PLS; FS; HPLC-DAD profile; VITAMIN-E; FLAVONOIDS;

D O I：

10.1021/jf901951z

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

In the present work, an environmentally friendly extraction process using subcritical conditions has been tested to obtain potential natural food ingredients from natural sources such as plants, fruits, spirulina, propolis, and tuber, with the scope of substituting synthetic antioxidants, which are subject to regulation restrictions and might be harmful for human health. A full characterization has been undertaken from the chemical and biochemical point of view to be able to understand their mechanism of action. Thus, an analytical method for profiling the compounds responsible for the antioxidant activity has been used, allowing the simultaneous determination of water-soluble vitamins, fat-soluble vitamins, phenolic compounds, carotenoids, and chlorophylls in a single run. This information has been integrated and analyzed using a chemometrical approach to correlate the bioactive compounds profile with the antioxidant activity and thus to be able to predict antioxidant activities of complex formulations. As a further step, a simplex centroid mixture design has been tested to find the optimal formulation and to calculate the effect of the interaction among individual extracts in the mixture.

引用

页码：787 / 792

页数：6

共 18 条

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[2]

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