Experimental and computational studies of determinants of membrane-protein folding

被引：26
作者：
Liang, J [1 ]
机构：
[1] Univ Illinois, Dept Bioengn, Chicago, IL 60607 USA
来源：
CURRENT OPINION IN CHEMICAL BIOLOGY | 2002年 / 6卷 / 06期
基金：
美国国家科学基金会;
关键词：
D O I：
10.1016/S1367-5931(02)00393-9
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent experiments and analysis have demonstrated the important roles of hydrogen bonding and polar-polar interactions in driving transmembrane helix-helix association. Further details of the energetics of helix-helix association and interhelical packing geometry are being mapped out. Many sequence motifs and a few spatial motifs promoting helical associations have also been identified.
引用
收藏
页码：878 / 884
页数：7
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