Large-Area SiPM Pixels (LASiPs) in SPECT

被引：2

作者：

Wunderlich, C. ^{[1
,2
]}

Guberman, D. ^{[1
,2
]}

Paoletti, R. ^{[1
,2
]}

Rugliancich, A. ^{[1
]}

Passeri, A. ^{[3
]}

机构：

[1] Ist Nazl Fis Nucl, Sez Pisa, Largo Bruno Pontecorvo 3 Edificio C, I-56126 Pisa, Italy

[2] Univ Siena, Dipartimento Sci Fis Terra & Ambiente, Via Roma 56, I-53100 Siena, Italy

[3] Univ Firenze, Dipartimento Sci Biomed Sperimentali & Clin SBSC, Viale Morgagni 50, I-50134 Florence, Italy

来源：

JOURNAL OF INSTRUMENTATION | 2022年 / 17卷 / 07期

关键词：

Gamma camera; SPECT; PET PET/CT; coronary CT angiography (CTA); Medical-mage reconstruction methods and algorithms; computer-aided diagnosis; Medical-image reconstruction methods and algorithms; computer-aided software; CAMERA;

D O I：

10.1088/1748-0221/17/07/C07021

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

A standard camera for Single Photon Emission Computed Tomography (SPECT) contains 50-100 photomultiplier tubes (PMTs) that occupy at least 50% of its volume. It is shielded by a thick layer of lead which makes it heavy and bulky. Replacing PMTs by silicon photomultipliers (SiPMs) could significantly reduce the weight and size of a SPECT camera. However, the main obstacle is the limited size of SiPMs: even with the largest commercially available SiPM of 6 x 6 mm(2) a few thousand channels would be needed to fill a camera. As a solution, we propose to use Large Area SiPM Pixels (LASiPs) which are built by summing the currents of several SiPMs into a single output. We developed a LASiP prototype summing 8 SiPMs using the MUSIC ASIC. To test the feasibility of using this solution in SPECT, we built a proof-of-concept micro camera that consisted of four of our LASiP prototypes coupled to a 40 x 40 x 8 mm(3) NaI(Tl) crystal. We were able to reconstruct simple images of a Tc-99m capillary with an intrinsic spatial resolution of similar to 2mm and an energy resolution of similar to 11.6%. We also simulated the system with Geant4, finding a good agreement with our experimental results. The simulations were extended to a larger camera, aiming to study the impact of pixel size, shape and noise.

引用

页数：10

共 15 条

[1] Characterization and assembly of near-ultraviolet SiPMs for the Schwarzschild-Couder medium-size telescope proposed for the CTA Observatory [J].

Adams, C. ;

Ambrosi, G. ;

Ambrosio, M. ;

Aramo, C. ;

Benbow, W. ;

Bertucci, B. ;

Bissaldi, E. ;

Bitossi, M. ;

Boiano, A. ;

Bonavolonta, C. ;

Bose, R. ;

Brill, A. ;

Buckley, J. H. ;

Caprai, M. ;

Covault, C. E. ;

Di Venere, L. ;

Feng, Q. ;

Fiandrini, E. ;

Gent, A. ;

Giglietto, N. ;

Giordano, F. ;

Halliday, R. ;

Hervet, O. ;

Hughes, G. ;

Humensky, T. B. ;

Ionica, M. ;

Jin, W. ;

Kaaret, P. ;

Kieda, D. ;

Kim, B. ;

Licciulli, F. ;

Loporchio, S. ;

Masone, V. ;

Meures, T. ;

Mode, B. A. W. ;

Mukherjee, R. ;

Okumura, A. ;

Otte, N. ;

Pantaleo, F. R. ;

Paoletti, R. ;

Petrashyk, A. ;

Powell, J. ;

Powell, K. ;

Ribeiro, D. ;

Rousselle, J. ;

Rugliancich, A. ;

Santander, M. ;

Shang, R. ;

Stevenson, B. ;

Stiaccini, L. .

HARD X-RAY, GAMMA-RAY, AND NEUTRON DETECTOR PHYSICS XXI, 2019, 11114

[2] SCINTILLATION CAMERA [J].

ANGER, HO .

REVIEW OF SCIENTIFIC INSTRUMENTS, 1958, 29 (01) :27-33

[3] Maximum-Likelihood Methods for Processing Signals From Gamma-Ray Detectors [J].

Barrett, Harrison H. ;

Hunter, William C. J. ;

Miller, Brian William ;

Moore, Stephen K. ;

Chen, Yichun ;

Furenlid, Lars R. .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2009, 56 (03) :725-735

[4] MUSIC: An 8 channel readout ASIC for SiPM arrays [J].

Gomez, Sergio ;

Gascon, David ;

Fernandez, Gerard ;

Sanuy, Andreu ;

Mauricio, Joan ;

Graciani, Ricardo ;

Sanchez, David .

OPTICAL SENSING AND DETECTION IV, 2016, 9899

[5] Large-Area SiPM Pixels (LASiPs): A cost-effective solution towards compact large SPECT cameras [J].

Guberman, D. ;

Paoletti, R. ;

Rugliancich, A. ;

Wunderlich, C. ;

Passeri, A. .

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 2021, 82 :171-184

[6] The Light-Trap: A novel concept for a large SiPM-based pixel for Very High Energy gamma-ray astronomy and beyond [J].

Guberman, D. ;

Cortina, J. ;

Ward, J. E. ;

Do Souto Espinera, E. ;

Hahn, A. ;

Mazin, D. .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2019, 923 :19-25

[7] Development of three silicon photomultiplier detector modules for the MAGIC telescopes for a performance comparison to PMTs [J].

Hahn, A. ;

Dettlaff, A. ;

Fink, D. ;

Mazin, D. ;

Mirzoyan, R. ;

Teshima, M. .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2018, 912 :259-263

[8] Development of clinical simultaneous SPECT/MRI [J].

Hutton, Brian F. ;

Occhipinti, Michele ;

Kuehne, Andre ;

Mathe, Domokos ;

Kovacs, Noemi ;

Waiczies, Helmar ;

Erlandsson, Kjell ;

Salvado, Debora ;

Carminati, Marco ;

Montagnani, Giovanni L. ;

Short, Susan C. ;

Ottobrini, Luisa ;

van Mullekom, Pieter ;

Piemonte, Claudio ;

Bukki, Tamas ;

Nyitrai, Zoltan ;

Papp, Zoltan ;

Nagy, Kalman ;

Niendorf, Thoralf ;

de Francesco, Irene ;

Fiorini, Carlo .

BRITISH JOURNAL OF RADIOLOGY, 2018, 91 (1081)

[9] Design of a SiPM-based cluster for the Large-Sized Telescope camera of the Cherenkov Telescope Array [J].

Mallamaci, M. ;

Baibussinov, B. ;

Busetto, G. ;

Corti, D. ;

De Angelis, A. ;

Di Pierro, F. ;

Doro, M. ;

Lessio, L. ;

Mariotti, M. ;

Rando, R. ;

Prandini, E. ;

Vallania, P. ;

Vigorito, C. F. .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2019, 936 :231-232

[10] Iterative reconstruction of detector response of an Anger gamma camera [J].

Morozov, A. ;

Solovov, V. ;

Alves, F. ;

Domingos, V. ;

Martins, R. ;

Neves, F. ;

Chepel, V. .

PHYSICS IN MEDICINE AND BIOLOGY, 2015, 60 (10) :4169-4184

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