A Palladium-Catalyzed Oxidative Cycloaromatization of Biaryls with Alkynes Using Molecular Oxygen as the Oxidant

被引：241

作者：

Shi, Zhuangzhi ^{[1
]}

Ding, Shengtao ^{[1
]}

Cui, Yuxin ^{[1
]}

Jiao, Ning ^{[1
,2
]}

机构：

[1] Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

[2] Chinese Acad Sci, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 42期

基金：

美国国家科学基金会;

关键词：

alkynes; biaryls; C-H activation; oxidation; palladium; POLYCYCLIC AROMATIC-HYDROCARBONS; H BOND FUNCTIONALIZATION; ACTIVE CARBAZOLE ALKALOIDS; INTERNAL ALKYNES; PHOTOPHYSICAL PROPERTIES; ORGANIC-CHEMICALS; GAMMA-CARBOLINES; C-C; ANNULATION; ACTIVATION;

D O I：

10.1002/anie.200903975

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Dual activation of C-H bonds has enabled the preparation of polycyclic aromatics from arylindoles and arylbenzofurans in the absence of a directing group, and with using O2 as the oxidant (see scheme). Synthetically and medicinally important polycyclic aromatics have been easily prepared, and some of the resulting polycyclic heteroaromatics exhibit intense fluorescence. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7895 / 7898

页数：4

共 74 条

[51] Palladium-catalyzed oxidation of organic chemicals with O2 [J].