Time from Positive Screening Fecal Occult Blood Test to Colonoscopy and Risk of Neoplasia

被引：30

作者：

Gellad, Ziad F. ^{[1
,2
]}

Almirall, Daniel ^{[2
,3
]}

Provenzale, Dawn ^{[1
,2
]}

Fisher, Deborah A. ^{[1
,2
]}

机构：

[1] Duke Univ, Med Ctr, Div Gastroenterol, Dept Med, Durham, NC 27710 USA

[2] Durham Vet Affairs Med Ctr, Ctr Hlth Serv Res Primary Care, Durham, NC USA

[3] Duke Univ, Med Ctr, Dept Biostat & Bioinformat, Durham, NC 27710 USA

来源：

DIGESTIVE DISEASES AND SCIENCES | 2009年 / 54卷 / 11期

关键词：

Colonic neoplasm; Occult blood; Colonoscopy; Follow-up studies; COLORECTAL-CANCER; DIAGNOSIS; SURVIVAL;

D O I：

10.1007/s10620-008-0653-8

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

There is no guideline defining the optimal time from a positive screening fecal occult blood test to follow-up colonoscopy. We reviewed records of 231 consecutive primary care patients who received a colonoscopy within 18 months of a positive fecal occult blood test. We examined the relationship between time to colonoscopy and risk of neoplasia on colonoscopy using a logistic regression analysis adjusting for potential confounders such as age, race, and gender. The mean time to colonoscopy was 236 days. Longer time to colonoscopy (OR = 1.10, P = 0.01) and older age (OR 1.04, P = 0.01) were associated with higher odds of neoplasia. The association of time with advanced neoplasia was positive, but not statistically significant (OR 1.07, P = 0.14). In this study, a longer interval to colonoscopy after fecal occult blood test was associated with an increased risk of neoplasia. Determining the optimal interval for follow-up is desirable and will require larger studies.

引用

页码：2497 / 2502

页数：6

共 23 条

[1] Does high body fatness increase the risk of presence and growth of colorectal adenomas followed up in situ for 3 years? [J].