Rotavirus infection in hospitalized children and estimates of disease burden in Kyrgyzstan, 2005-2007

被引：9

作者：

Flem, Elmira T. ^{[1
]}

Kasymbekova, Kaliya T. ^{[2
]}

Vainio, Kirsti ^{[1
]}

Gentsch, Jon ^{[3
]}

Abdikarimov, Sabirjan T. ^{[2
]}

Glass, Roger I. ^{[4
]}

Bresee, Joseph S. ^{[3
]}

机构：

[1] Norwegian Inst Publ Hlth, Div Infect Dis Control, N-0403 Oslo, Norway

[2] Minist Hlth, Dept State Sanit Epidemiol Surveillance, Bishkek, Kyrgyzstan

[3] Ctr Dis Control & Prevent, Atlanta, GA USA

[4] NIH, Fogarty Int, Bethesda, MD 20892 USA

来源：

VACCINE | 2009年 / 27卷

关键词：

Rotavirus; Gastroenteritis; Epidemiology; POPULATION; EFFICACY; VACCINE; DEATHS; SAFETY;

D O I：

10.1016/j.vaccine.2009.08.087

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To estimate the rotavirus-associated burden in Kyrgyzstan, we conducted hospital surveillance among children <5 years old with diarrhoea during 2005-2007. Of 3756 children hospitalized with diarrhoea, 26% had rotavirus detected in stool samples by an enzyme immunoassay. The virus genotype G1P[8] was identified in 60% of 190 characterized samples from 2005 to 2006. The estimated risk for rotavirus hospitalization by age 5 years was 1 in 28 children. One quarter of all gastroenteritis hospitalizations in children <5 years old in Kyrgyzstan may be attributable to rotavirus. Rotavirus vaccination could be an important health intervention to reduce the burden of rotavirus gastroenteritis. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：F35 / F39

页数：5

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