Recent advancements in the SQUID magnetospinogram system

被引:20
作者
Adachi, Yoshiaki [1 ]
Kawai, Jun [1 ]
Haruta, Yasuhiro [1 ]
Miyamoto, Masakazu [1 ]
Kawabata, Shigenori [2 ]
Sekihara, Kensuke [2 ]
Uehara, Gen [1 ]
机构
[1] Kanazawa Inst Technol, Appl Elect Lab, Kanazawa, Ishikawa, Japan
[2] Tokyo Med & Dent Univ, Dept Adv Technol Med, Tokyo, Japan
基金
日本学术振兴会;
关键词
SQUID; biomagnetism; magnetospinogram; SPINAL-CORD; BIOMAGNETOMETER SYSTEM; MAGNETIC-FIELD; NERVE; NOISE; VISUALIZATION; CONDUCTION;
D O I
10.1088/1361-6668/aa66b3
中图分类号
O59 [应用物理学];
学科分类号
摘要
In this study, a new superconducting quantum interference device (SQUID) biomagnetic measurement system known as magnetospinogram (MSG) is developed. The MSG system is used for observation of a weak magnetic field distribution induced by the neural activity of the spinal cord over the body surface. The current source reconstruction for the observed magnetic field distribution provides noninvasive functional imaging of the spinal cord, which enables medical personnel to diagnose spinal cord diseases more accurately. The MSG system is equipped with a uniquely shaped cryostat and a sensor array of vector-type SQUID gradiometers that are designed to detect the magnetic field from deep sources across a narrow observation area over the body surface of supine subjects. The latest prototype of the MSG system is already applied in clinical studies to develop a diagnosis protocol for spinal cord diseases. Advancements in hardware and software for MSG signal processing and cryogenic components aid in effectively suppressing external magnetic field noise and reducing the cost of liquid helium that act as barriers with respect to the introduction of the MSG system to hospitals. The application of the MSG system is extended to various biomagnetic applications in addition to spinal cord functional imaging given the advantages of the MSG system for investigating deep sources. The study also includes a report on the recent advancements of the SQUID MSG system including its peripheral technologies and wide-spread applications.
引用
收藏
页数:16
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