Beta cell miR-125b controls glucose homeostasis by targeting lysosomal and mitochondrial genes

被引：0
|
作者：
Martinez-Sanchez, A. [1 ]
Cheung, R. [1 ]
Pizza, G. [1 ]
Rolando, D. [1 ]
Chabosseau, P. [1 ]
Tomas, A. [1 ]
Salowska, A. [1 ]
Burgoyne, T. [2 ]
Leclerc, I. [1 ]
Rutter, G. A. [1 ]
机构：
[1] Imperial Coll London, London, England
[2] UCL, London, England
来源：
DIABETOLOGIA | 2021年 / 64卷 / SUPPL 1期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
304
引用
收藏
页码：158 / 158
页数：1
相关论文
共 50 条
  • [1] miR-125b impairs beta cell function in vivo by targeting lysosomal and mitochondrial genes
    Cheung, R.
    Pizza, G.
    Chabosseau, P.
    Rolando, D.
    Salowska, A.
    Burgoyne, T.
    Leclerc, I.
    Tomas, A.
    Rutter, G. A.
    Martinez-Sanchez, A.
    DIABETIC MEDICINE, 2021, 38
  • [2] MIR-125B CONTROLS MITOCHONDRIAL FUNCTIONS AND DYNAMICS IN MONOCYTES
    Duroux-Richard, I.
    Roubert, C.
    Ammari, M.
    Presumey, J.
    Gruen, J. R.
    Haeupl, T.
    Gruetzkau, A.
    Lecellier, C-H
    Jorgensen, C.
    Apparailly, F.
    ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 : A80 - A81
  • [3] Glucose-controlled miR-125b regulates beta cell function
    Cheung, R.
    Pizza, G.
    Nguyen-Tu, M. -S.
    Chabosseau, P.
    Rolando, D.
    Cebola, I.
    Marchetti, P.
    Shapiro, J.
    Piemonti, L.
    Sakamoto, K.
    Smith, D.
    Rutter, G.
    Martinez-Sanchez, A.
    DIABETOLOGIA, 2019, 62 : S219 - S219
  • [4] miR-125b controls monocyte adaptation to inflammation through mitochondrial metabolism and dynamics
    Duroux-Richard, Isabelle
    Roubert, Christine
    Ammari, Meryem
    Presumey, Jessy
    Gruen, Joachim R.
    Haeupl, Thomas
    Gruetzkau, Andreas
    Lecellier, Charles-Henri
    Boitez, Valerie
    Codogno, Patrice
    Escoubet, Johanna
    Pers, Yves-Marie
    Jorgensen, Christian
    Apparailly, Florence
    BLOOD, 2016, 128 (26) : 3125 - 3136
  • [5] miR-125b is a new regulator of pancreatic beta cell function
    Cheung, R.
    Rolando, D.
    Chabosseau, P.
    Sakamoto, K.
    Smith, D. M.
    Rutter, G. A.
    Martinez-Sanchez, A.
    DIABETIC MEDICINE, 2018, 35 : 47 - 47
  • [6] Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function
    Cheung, Rebecca
    Pizza, Grazia
    Chabosseau, Pauline
    Rolando, Delphine
    Tomas, Alejandra
    Burgoyne, Thomas
    Wu, Zhiyi
    Salowka, Anna
    Thapa, Anusha
    Macklin, Annabel
    Cao, Yufei
    Nguyen-Tu, Marie-Sophie
    Dickerson, Matthew T.
    Jacobson, David A.
    Marchetti, Piero
    Shapiro, James
    Piemonti, Lorenzo
    de Koning, Eelco
    Leclerc, Isabelle
    Bouzakri, Karim
    Sakamoto, Kei
    Smith, David M.
    Rutter, Guy A.
    Martinez-Sanchez, Aida
    DIABETES, 2022, 71 (07) : 1525 - 1545
  • [7] miR-125b Is Regulated by Glucose via AMPK and Impairs β-Cell Function
    Cheung, Rebecca
    Pizza, Grazia
    Rolando, Delphine M.
    Chabosseau, Pauline L.
    Nguyen-Tu, Marie-Sophie
    Leclerc, Isabelle
    Rutter, Guy A.
    Martinez-Sanchez, Aida
    DIABETES, 2019, 68
  • [8] miR-125b promotes cell proliferation by directly targeting Lin28 in glioblastoma stem cells with low expression levels of miR-125b
    Wan, Yi
    Sun, Guan
    Wang, Zhimin
    Guo, Jun
    Shi, Lei
    NEUROREPORT, 2014, 25 (05) : 289 - 296
  • [9] miR-125b inhibits goblet cell differentiation in allergic airway inflammation by targeting SPDEF
    Liu, Zhaoe
    Chen, Xing
    Wu, Qiaoling
    Song, Jia
    Wang, Lijun
    Li, Gang
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2016, 782 : 14 - 20
  • [10] MiR-125b acts as a tumor suppressor of melanoma by targeting NCAM
    Wang, Tao
    Li, Wei
    Yin, Shuang
    Chen, Weihua
    JOURNAL OF BUON, 2021, 26 (01): : 182 - 188
12345