A New Sesquiterpenoid-Geranylbenzene Conjugate from the Roots of Lindera chunii

被引：2

作者：

Wen, Songsong ^{[1
,2
]}

Li, Qiyang ^{[2
]}

Liu, Qi ^{[2
]}

Dou, Yanli ^{[2
]}

Niu, Chong ^{[2
]}

Xu, Yuwen ^{[2
]}

Zhang, Na ^{[1
]}

Wang, Weijian ^{[2
]}

机构：

[1] Shandong Univ, Dept Pharmaceut, Sch Pharmaceut Sci, Key Lab Chem Biol,Minist Educ,Cheeloo Coll Med, Jinan 250012, Peoples R China

[2] Shandong Inst Food & Drug Control, NMPA Key Lab Res & Evaluat Gener Drugs, Shandong Res Ctr Engn & Technol Consistency Evalu, Jinan 250101, Peoples R China

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2022年 / 58卷 / 06期

关键词：

Lindera chunii; sesquiterpenoid; lindechunisin A; cytotoxic activity;

D O I：

10.1007/s10600-022-03863-y

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Lindechunisin A, a new sesquiterpenoid-geranylbenzene conjugate, was isolated from the roots of Lindera chunii. The structure of this compound was characterized by extensive spectroscopic methods. The cytotoxicity evaluation revealed that lindechunisin A showed moderate cytotoxic activity against the HeLa cell line with IC50 value of 52.60 +/- 4.22 mu M.

引用

页码：1045 / 1047

页数：3

共 9 条

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