Genetic mapping and characterization of novel mutations which suppress the effect of a relC mutation on antibiotic production in Streptomyces coelicolor A3(2)

被引：8

作者：

Ochi, K ^{[1
]}

Hosoya, Y ^{[1
]}

机构：

[1] Natl Food Res Inst, Tsukuba, Ibaraki 3058642, Japan

来源：

JOURNAL OF ANTIBIOTICS | 1998年 / 51卷 / 06期

关键词：

D O I：

10.7164/antibiotics.51.592

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

[No abstract available]

引用

页码：592 / 595

页数：4

共 10 条

[1] The ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2) play's a conditional role in antibiotic production and morphological differentiation
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Bibb, M
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[2] Cloning, characterization and disruption of a (p)ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2)
Chakraburtty, R
White, J
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Bibb, M
[J]. MOLECULAR MICROBIOLOGY, 1996, 19 (02) : 357 - 368
[3] A novel method for improving Streptomyces coelicolor A3(2) for production of actinorhodin by introduction of rpsL (Encoding ribosomal protein S12) mutations conferring resistance to streptomycin
Hesketh, A
Ochi, K
[J]. JOURNAL OF ANTIBIOTICS, 1997, 50 (06) : 532 - 535
[4] Hopwood D.A., 1985, GENETIC MANIPULATION
[5] HOPWOOD DA, 1974, HDB GENETICS, V1, P237
[6] METABOLIC INITIATION OF DIFFERENTIATION AND SECONDARY METABOLISM BY STREPTOMYCES-GRISEUS - SIGNIFICANCE OF THE STRINGENT RESPONSE (PPGPP) AND GTP CONTENT IN RELATION TO A FACTOR
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[J]. JOURNAL OF BACTERIOLOGY, 1987, 169 (08) : 3608 - 3616
[7] A RELAXED (REL) MUTANT OF STREPTOMYCES-COELICOLOR A3(2) WITH A MISSING RIBOSOMAL-PROTEIN LACKS THE ABILITY TO ACCUMULATE PPGPP, A-FACTOR AND PRODIGIOSIN
OCHI, K
[J]. JOURNAL OF GENERAL MICROBIOLOGY, 1990, 136 : 2405 - 2412
[8] Ochi K, 1997, MOL GEN GENET, V256, P488
[9] A set of ordered cosmids and a detailed genetic and physical map for the 8 Mb Streptomyces coelicolor A3(2) chromosome
Redenbach, M
Kieser, HM
Denapaite, D
Eichner, A
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Hopwood, DA
[J]. MOLECULAR MICROBIOLOGY, 1996, 21 (01) : 77 - 96
[10] Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor A3(2)
Shima, J
Hesketh, A
Okamoto, S
Kawamoto, S
Ochi, K
[J]. JOURNAL OF BACTERIOLOGY, 1996, 178 (24) : 7276 - 7284

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