Benefits of breastfeeding in cystic fibrosis:: A single-centre follow-up survey

被引:26
作者
Colombo, Carla
Costantini, Diana
Zazzeron, Laura
Faelli, Nadia
Russo, Maria Chiara
Ghisleni, Diana
Gatelli, Italo
Giovannini, Marcello
Riva, Enrica
Zetterstrom, Rolf
Agostoni, Carlo
机构
[1] Univ Milan, Fdn IRCCS Polyclin, CF Ctr, Inst Pediat & Neonatol, I-20122 Milan, Italy
[2] Univ Milan, San Paolo Hosp, Dept Pediat, I-20122 Milan, Italy
[3] Karolinska Univ Hosp, Stockholm, Sweden
关键词
cystic fibrosis; human milk; infections; lung function; pancreatic function;
D O I
10.1111/j.1651-2227.2007.00397.x
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Aim: To study the effect of breastfeeding (BF) on growth, lung function and number of infections during the first 3 years of life in children with cystic fibrosis (CF). Material and methods: One hundred forty-six CF patients, 5-18 years old, were recruited at their annual care visit. Information about infant feeding, psychosocial and socioeconomic conditions and smoking exposure was obtained by interviews. Anthropometric parameters at 1 year of age and the number of infections and hospitalisations during the first 3 years of life were obtained from clinical charts. Anthropometrics and pulmonary function parameters were obtained at enrolment. Results: In CF patients, particularly those with pancreatic insufficiency, the prevalence of BF was lower than the general Italian population. After multivariate analysis patients with prolonged BF showed higher values of CED expiratory volume in 1 sec (FEV-1) (p = 0.001) and a lower number of infections during the first 3 years of life (p = 0.098). Conclusion: Prolonged BF is beneficial in children with CF and may protect them against decline of pulmonary function. Particular attention should be paid to promote BF in infants with CF.
引用
收藏
页码:1228 / 1232
页数:5
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