Advances in pediatric asthma in 2014: Moving toward a population health perspective

被引:16
作者
Szefler, Stanley J. [1 ,2 ]
机构
[1] Childrens Hosp Colorado, Dept Pediat, Breathing Inst, Pediat Asthma Res Program,Sect Pediat Pulm Med, Aurora, CO 80045 USA
[2] Univ Colorado Denver, Sch Medicine, Dept Pediat, Aurora, CO USA
基金
美国国家卫生研究院;
关键词
Airway remodeling; asthma; asthma control; asthma exacerbations; early intervention in asthma; biomarkers; environment; genetics; inhaled corticosteroids; leukotriene receptor antagonists; long-acting beta-adrenergic agonists; personalized medicine; severe asthma; therapeutics; GENOME-WIDE ASSOCIATION; CHILDHOOD ASTHMA; AIR-POLLUTION; LUNG-FUNCTION; ADULT ASTHMA; BRONCHODILATOR RESPONSE; RESPIRATORY SYMPTOMS; PRESCHOOL-CHILDREN; WHEEZE PHENOTYPES; IMMUNE-RESPONSES;
D O I
10.1016/j.jaci.2014.12.1921
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Last year's "Advances in pediatric asthma in 2013: Coordinating asthma care" concluded that, "Enhanced communication systems will be necessary among parents, clinicians, health care providers and the pharmaceutical industry so that we continue the pathway of understanding the disease and developing new treatments that address the unmet needs of patients who are at risk for severe consequences of unchecked disease persistence or progression." This year's summary will focus on further advances in pediatric asthma related to prenatal and postnatal factors altering the natural history of asthma, assessment of asthma control, and new insights regarding the management of asthma in children as indicated in Journal of Allergy and Clinical Immunology publications in 2014. A major theme of this review is how new research reports can be integrated into medical communication in a population health perspective to assist clinicians in asthma management. The asthma specialist is in a unique position to convey important messages to the medical community related to factors that influence the course of asthma, methods to assess and communicate levels of control, and new targets for intervention, as well as new immunomodulators. By enhancing communication among patients, parents, primary care physicians, and specialists within provider systems, the asthma specialist can provide timely information that can help to reduce asthma morbidity and mortality.
引用
收藏
页码:644 / 652
页数:9
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