Anti-Mullerian hormone: Player and marker of folliculogenesis

被引:5
作者
da Silva, A. -L Berwanger [1 ]
Even, M. [1 ]
Grynberg, M. [1 ]
Gallot, V. [1 ]
Frydman, R. [1 ]
Fanchin, R. [1 ]
机构
[1] Univ Paris Sud, Hop Antoine Beclere, INSERM, Serv Gynecol Obstet & Med Reprod,U782,AP HP, F-92141 Clamart, France
来源
GYNECOLOGIE OBSTETRIQUE & FERTILITE | 2010年 / 38卷 / 7-8期
关键词
Anti-Mullerian hormone; Ovarian reserve; Ovarian stimulation; Folliculogenesis; Antral follicle count; IVF; FOLLICLE-STIMULATING-HORMONE; ASSISTED REPRODUCTIVE TECHNOLOGY; POLYCYSTIC-OVARY-SYNDROME; IN-VITRO FERTILIZATION; INHIBITING SUBSTANCE LEVELS; ANTIMULLERIAN HORMONE; MENSTRUAL-CYCLE; MOUSE OVARY; TRANSVAGINAL ULTRASONOGRAPHY; GRANULOSA-CELLS;
D O I
10.1016/j.gyobfe.2010.05.002
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
All indicates that anti-Mullerian hormone (AMH), though initially studied for its importance on male development, plays an inhibiting role on the initial and cyclic processes of follicular recruitment. The aspects involved in its regulation are still poorly understood, but the oocyte, some steroids, and follicular development itself seem to be involved. In addition, AMH has become an important clinical marker of ovarian functioning for many reasons, including its exclusive production by granulosa follicles at many stages of development, its probable FSH independence, its low inter and intracycle variability and its reliable quantitative (qualitative?) relationship with ovarian follicles and their response to exogenous FSH. The growing interest in ovarian AMH incited us to review some important fundamental and clinical publications in this field. (C) 2010 Published by Elsevier Masson SAS.
引用
收藏
页码:471 / 474
页数:4
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