SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF S-ALKYL DERIVATIVES OF 1,3,4-OXADIAZOLE CARRYING BENZOTHIAZOLE CORE

被引:0
作者
Kadoor, Sushma [1 ]
Kalluraya, Balakrishna [1 ]
Shetty, Shobhitha [1 ]
Ballal, Mamatha [2 ]
Shetty, Vignesh [2 ]
机构
[1] Mangalore Univ, Dept Studies Chem, Mangalagangothri 574199, Karnataka, India
[2] Manipal Univ, Dept Microbiol, Manipal, Karnataka, India
关键词
AGENTS;
D O I
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new series of s-alkyl derivatives of 1,3,4-oxadiazole carrying benzothiazole moiety (5a-I) has been synthesized starting from 6-amino benzothiazole. The structures of these newly synthesized compounds were elucidated by elemental analysis, 'H NMR and mass spectral data. Also these compounds were evaluated for their antibacterial activity against the bacteria Pseudomonas, Staphylcoccus aureus, Enterococcus, Eschericia co/land antifungal activity against Candida albicans.
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页码:295 / 298
页数:4
相关论文
共 17 条
  • [1] Alam M, 2004, INDIAN J HETEROCY CH, V13, P361
  • [2] Amit B.N., 2000, INDIAN J HETEROCY CH, V9, P309
  • [3] Burbuliene Milda Malvina, 2004, Farmaco (Lausanne), V59, P767, DOI 10.1016/j.farmac.2004.05.007
  • [4] Design, synthesis, and biological evaluation of novel 1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted benzylamino-2-propanols
    Chai, Xiaoyun
    Zhang, Jun
    Yu, Shichong
    Hu, Honggang
    Zou, Yan
    Zhao, Qingjie
    Dan, Zhigang
    Zhang, Dazhi
    Wu, Qiuye
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (06) : 1811 - 1814
  • [5] Synthesis and fungicidal activity against Rhizoctonia solani of 2-alkyl (alkylthio)-5-pyrazolyl-1,3,4-oxadiazoles (thiadiazoles)
    Chen, HS
    Li, ZM
    Han, YF
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2000, 48 (11) : 5312 - 5315
  • [6] Ezaei Z. R., 2009, EUR J MED CHEM, V44, P3064
  • [7] Ghoneim KM, 1998, INDIAN J CHEM B, V37, P904
  • [8] Antitumor benzothiazoles. 14. Synthesis and in vitro biological properties of fluorinated 2-(4-aminophenyl)benzothiazoles
    Hutchinson, I
    Chua, MS
    Browne, HL
    Trapani, V
    Bradshaw, TD
    Westwell, AD
    Stevens, MFG
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2001, 44 (09) : 1446 - 1455
  • [9] Jakubkiene Virginija, 2003, Farmaco (Lausanne), V58, P323, DOI 10.1016/S0014-827X(02)00022-8
  • [10] Antimycobacterial activity of new 3-substituted 5-(pyridin-4-yl)-3H-1,3,4-oxadiazol-2-one and 2-thione derivatives.: Preliminary molecular modeling investigations
    Mamolo, MG
    Zampieri, D
    Vio, L
    Fermeglia, M
    Ferrone, M
    Pricl, S
    Scialino, G
    Banfi, E
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2005, 13 (11) : 3797 - 3809