Shiga Toxin Producing Escherichia coli

被引:76
作者
Bryan, Allen [1 ]
Youngster, Ilan [2 ]
McAdam, Alexander J. [3 ]
机构
[1] Beth Israel Deaconess Med Ctr, Dept Pathol, Div Lab Med, Boston, MA 02215 USA
[2] Boston Childrens Hosp, Div Infect Dis, Boston, MA 02115 USA
[3] Boston Childrens Hosp, Dept Lab Med, Boston, MA 02115 USA
关键词
Shiga toxin-producing Escherichia coli; Enterohemorrhagic Escherichia coli; Escherichia coli O157; Gastroenteritis; HEMOLYTIC-UREMIC SYNDROME; REAL-TIME PCR; SORBITOL-MACCONKEY MEDIUM; POLYMERASE-CHAIN-REACTION; HEMORRHAGIC COLITIS; UNITED-STATES; E.-COLI; STOOL SAMPLES; MULTIPLEX PCR; TELLURITE RESISTANCE;
D O I
10.1016/j.cll.2015.02.004
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Shiga toxin producing Escherichia coli (STEC) is among the common causes of foodborne gastroenteritis. STEC is defined by the production of specific toxins, but within this pathotype there is a diverse group of organisms. This diversity has important consequences for understanding the pathogenesis of the organism, as well as for selecting the optimum strategy for diagnostic testing in the clinical laboratory. This review includes discussions of the mechanisms of pathogenesis, the range of manifestations of infection, and the several different methods of laboratory detection of Shiga toxin-producing E coli.
引用
收藏
页码:247 / +
页数:27
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