Self-assembled bioconjugates for biochip technologies

This article gives all overview on current research ill the area of self-assenibled bioconjugates comprised of DNA-, protein-and nanoparticle building blocks. In particular, the highly specific molecular recognition capabilities of short DNA oligomers are utilized to organize inorganic nanoparticles and proteins, thereby allowing for the fabrication of functional biomolecular hybrid devices. These devices are employed, for instance, to generate programmable biomaterials and probes for bioanalytical methods, such as immunological assays and microarray technologies.