Impact of social interactions in the community on the transmission of tuberculosis in a high incidence area

被引:85
作者
Classen, CN
Warren, R
Richardson, M
Hauman, JH
Gie, RP
Ellis, JHP
van Helden, PD
Beyers, N
机构
[1] Univ Stellenbosch, Dept Paediat & Child Hlth, ZA-7505 Tygerberg, South Africa
[2] Univ Western Cape, Dept Anthropol Sociol, ZA-7535 Bellville, South Africa
[3] Univ Stellenbosch, Dept Biochem Med, MRC, Ctr Cellular & Mol Biol, ZA-7600 Stellenbosch, South Africa
关键词
tuberculosis; transmission; social interaction;
D O I
10.1136/thx.54.2.136
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Background-Tuberculosis (TB) is transmitted by close contact with an infectious person. It is assumed that close contact occurs amongst household members and that contact outside the house is "casual" and does not play a major role in the transmission of TB. Methods-This study was conducted in an impoverished area with a high incidence of TB and a low! HIV seropositive prevalence. Thirty three households with 84 TB patients were identified between February 1993 and April 1996 and the transmission of TB was studied by combining Mycobacterium tuberculosis fingerprinting with in depth sociological interviews. Results-Forty two strain genotypes were identified in the 84 patients. In 15 households all the patients had identical strains, in nine households all the patients had different strains, and in nine households some patients had identical strains and one had a different strain. In 26 houses at least one patient had a strain which formed part of a larger community cluster and in 12 of these households the patient(s) had contact with a community member who had the identical strain. In 58% of the cases the contact took place while drinking in social groups. Conclusion-In high incidence areas contact outside the household may be important for the transmission of Tn. This contact often takes place during recreation which, in the case of this study of impoverished people, consisted of drinking in social groups. Social interaction patterns should be studied and understood for effective implementation of control strategies.
引用
收藏
页码:136 / 140
页数:5
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