Absence of Epstein-Barr virus in esophageal squamous cell carcinoma

被引：14

作者：

Sunpaweravong, S ^{[1
]}

Mitarnun, W

Puttawibul, P

机构：

[1] Prince Songkla Univ, Songklanagarind Hosp, Dept Surg, Hat Yai 90110, Thailand

[2] Prince Songkla Univ, Songklanagarind Hosp, Dept Pathol, Hat Yai 90110, Thailand

来源：

DISEASES OF THE ESOPHAGUS | 2005年 / 18卷 / 06期

关键词：

Epstein-Barr virus; esophageal squamous cell carcinoma; etiology;

D O I：

10.1111/j.1442-2050.2005.00522.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

It is strongly suspected that the Epstein-Barr virus (EBV) plays a role in the genesis of nasopharyngeal and gastric carcinoma. The aim of this study was to search for such a connection between esophageal squamous cell carcinoma (ESCC) and EBV. We investigated 104 surgically resected esophageal cancers using in situ hybridization (ISH) for EBV-encoded RNA (EBER). We found no EBER-positive cancer cells in any tests, although there were five samples in which EBER-positive tumor-infiltrating lymphocytes (TILs) were found. We conclude from this study that EBV is not associated with ESCC.

引用

页码：398 / 399

页数：2