Phase-Amplitude Coupling: A General Mechanism for Memory Processing and Synaptic Plasticity?

被引：73

作者：

Bergmann, Til O. ^{[1
,2
]}

Born, Jan ^{[1
,3
]}

机构：

[1] Univ Tubingen, Inst Med Psychol & Behav Neurobiol, D-72076 Tubingen, Germany

[2] Univ Tubingen, Dept Neurol & Stroke, Hertie Inst Clin Brain Res, D-72076 Tubingen, Germany

[3] Univ Tubingen, Ctr Integrat Neurosci, D-72076 Tubingen, Germany

来源：

NEURON | 2018年 / 97卷 / 01期

关键词：

OSCILLATIONS; HIPPOCAMPUS; SPINDLES;

D O I：

10.1016/j.neuron.2017.12.023

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In this issue of Neuron, Helfrich et al. (2017) demonstrate that phase-amplitude coupling (PAC) between slow oscillations and spindles is crucial for memory consolidation, and shifts in its phase relationship may explain age-related deficits in memory performance. These results also suggest a more general function of PAC in synaptic plasticity.

引用

收藏

页码：10 / 13

页数：5

相关论文

共 10 条

[1] The role of phase synchronization in memory processes [J].

Fell, Juergen ;

Axmacher, Nikolai .

NATURE REVIEWS NEUROSCIENCE, 2011, 12 (02) :105-U1500

[2] Old Brains Come Uncoupled in Sleep: Slow Wave-Spindle Synchrony, Brain Atrophy, and Forgetting [J].

Helfrich, Randolph F. ;

Mander, Bryce A. ;

Jagust, William J. ;

Knight, Robert T. ;

Walker, Matthew P. .

NEURON, 2018, 97 (01) :221-+

[3] BIDIRECTIONAL SYNAPTIC PLASTICITY INDUCED BY A SINGLE BURST DURING CHOLINERGIC THETA-OSCILLATION IN CA1 IN-VITRO [J].

HUERTA, PT ;

LISMAN, JE .

NEURON, 1995, 15 (05) :1053-1063

[4] Thalamic Spindles Promote Memory Formation during Sleep through Triple Phase-Locking of Cortical, Thalamic, and Hippocampal Rhythms [J].

Latchoumane, Charles-Francois V. ;

Ngo, Hong-Viet V. ;

Born, Jan ;

Shin, Hee-Sup .

NEURON, 2017, 95 (02) :424-+

[5] Plasticity during Sleep Is Linked to Specific Regulation of Cortical Circuit Activity [J].

Niethard, Niels ;

Burgalossi, Andrea ;

Born, Jan .

FRONTIERS IN NEURAL CIRCUITS, 2017, 11

[6] ABOUT SLEEP'S ROLE IN MEMORY [J].

Rasch, Bjoern ;

Born, Jan .

PHYSIOLOGICAL REVIEWS, 2013, 93 (02) :681-766

[7] Cortical dendritic activity correlates with spindle-rich oscillations during sleep in rodents [J].

Seibt, Julie ;

Richard, Clement J. ;

Sigl-Gloeckner, Johanna ;

Takahashi, Naoya ;

Kaplan, David I. ;

Doron, Guy ;

de Limoges, Denis ;

Bocklisch, Christina ;

Larkum, Matthew E. .

NATURE COMMUNICATIONS, 2017, 8

[8] Hierarchical nesting of slow oscillations, spindles and ripples in the human hippocampus during sleep [J].

Staresina, Bernhard P. ;

Bergmann, Ti Ole ;

Bonnefond, Mathilde ;

van der Meij, Roemer ;

Jensen, Ole ;

Deuker, Lorena ;

Elger, Christian E. ;

Axmacher, Nikolai ;

Fell, Juergen .

NATURE NEUROSCIENCE, 2015, 18 (11) :1679-1686

[9] Theta-associated high-frequency oscillations (110-160 Hz) in the hippocampus and neocortex [J].

Tort, Adriano B. L. ;

Scheffer-Teixeira, Robson ;

Souza, Bryan C. ;

Draguhn, Andreas ;

Brankack, Jurij .

PROGRESS IN NEUROBIOLOGY, 2013, 100 :1-14

[10]

Zrenner C., 2017, Brain Stimulation, P1