The association between the COMT gene Val158Met polymorphism and preschoolers' autobiographical memory details and narrative cohesiveness

被引:2
作者
Tougu, P. [1 ]
Vaht, M. [1 ]
Tulviste, T. [1 ]
Veidebaum, T. [2 ]
Harro, J. [1 ]
机构
[1] Univ Tartu, Inst Psychol, Naituse 2, EE-50409 Tartu, Estonia
[2] Natl Inst Hlth Dev, Hiiu 42, EE-11619 Tallinn, Estonia
关键词
Longitudinal study; COMT gene; Episodic memory; Narrative cohesiveness; Preschoolers; CATECHOL-O-METHYLTRANSFERASE; MATERNAL REMINISCING STYLE; MOTHER-CHILD CONVERSATIONS; EPISODIC MEMORY; COGNITIVE FUNCTION; ENZYME-ACTIVITY; WORKING-MEMORY; LANGUAGE; GENDER; GENOTYPE;
D O I
10.1016/j.cogdev.2016.06.002
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
A longitudinal study addressed the effect of COMT gene Val(158)Met polymorphism on memory narratives of children. The effects of sex and maternal education were also studied. The total sample consisted of 486 children (48.9% boys), who were 4 years old during the first and 6 six years old during the second wave. COMT gene Val(158)Met polymorphism had an effect on the number of memory details in autobiographical memories with Met/Met homozygotes providing more details than the children with the Val/Met genotype. A genotype by maternal education interaction was observed at the age of four, but not at the age of six: Met/Met genotype children in the lower maternal educational attainment group had more detailed memories at the age of four than their Val/Met counterparts. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码:181 / 188
页数:8
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