Transarterial Ethanol Ablation Combined with Transarterial Chemoembolization for Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

被引：7
作者：
Yang, Biao [1 ,2 ]
You, Xin [1 ,2 ]
Yuan, Min Lan [3 ]
Qin, Tian Qiang [5 ]
Duan, Lin Jia [4 ]
He, Jiao [4 ]
Fei, Ze Jun [4 ]
Zhou, Xuan [4 ]
Zan, Rui Yu [1 ,2 ]
Liao, Zheng Yin [1 ,2 ]
机构：
[1] Sichuan Univ, West China Med Sch, West China Hosp, Dept Abdominal Oncol,Canc Ctr, Chengdu, Peoples R China
[2] Sichuan Univ, West China Med Sch, West China Hosp, State Key Lab Biotherapy, Chengdu, Peoples R China
[3] Sichuan Univ, West China Med Sch, West China Hosp, Ctr Psychiat, Chengdu, Peoples R China
[4] Sichuan Univ, West China Med Sch, West China Hosp, Dept Radiol, Chengdu, Peoples R China
[5] Sichuan Univ, West China Med Sch, West China Hosp, Chinese Evidence Based Med Ctr, Chengdu, Peoples R China
来源：
HEPATITIS MONTHLY | 2016年 / 16卷 / 08期
关键词：
Portal Vein Tumor Thrombosis; Ethanol; Transarterial Ethanol Ablation; Hepatocellular Carcinoma; Cone-Beam Computed Tomography; TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; CLINICOPATHOLOGICAL CHARACTERISTICS; NATURAL-HISTORY; EMBOLIZATION; RESECTION; INJECTION; CRITERIA; OUTCOMES; THERAPY; MIXTURE;
D O I：
10.5812/hepatmon.37584
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Background: The prognosis for hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) is extremely poor. Objectives: This study aimed to evaluate the safety and effectiveness of transarterial ethanol ablation (TEA) for the treatment of HCC with PVTT. Methods: Patients were treated with TEA for PVTT under cone-beam computed tomography and traditional transarterial chemoembolization (TACE) with epirubicin for intrahepatic lesions. Results: Seventeen men were successfully treated with TACE plus TEA. The mean overall survival was 18.3 +/- 9.0 months (95% CI: 13.7 -3.0 months). The quality of life (QoL) score increased from 56.9 +/- 15.7 before the procedure to 88.5 +/- 11.7 at 4 weeks after the procedure. Lipiodol accumulation grades of 3, 2, 1, and 0 were obtained in 3 (17.6%), 8 (47.1%), 6 (35.3%), and 0 (0%) patients, respectively. Conclusions: TEA is a safe and effective method for treating patients with PVTT, offering advantages for QoL, response rate after TEA, and OS.
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页数：8
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