Calculation of depth-dependent elemental concentration with X-ray fluorescence using a layered calibration method

被引：4
作者：
Gherase, M. R. [1 ]
Fleming, D. E. B. [1 ]
机构：
[1] Mt Allison Univ, Dept Phys, Sackville, NB E4L 1E6, Canada
来源：
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS | 2011年 / 269卷 / 10期
基金：
加拿大自然科学与工程研究理事会; 加拿大健康研究院;
关键词：
X-ray fluorescence; Calibration; Depth-dependent concentration; CONFOCAL MU-XRF; FUNDAMENTAL PARAMETERS; POLYESTER RESIN; SKIN PHANTOMS; SAMPLES; PAINT;
D O I：
10.1016/j.nimb.2011.02.086
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
Depth-dependent elemental concentration can be assessed using either multiple-angle or confocal X-ray fluorescence (XRF) measurements. This work presents a different approach based on a layered calibration method. The depth-dependent elemental concentration was modeled as multiple layers of uniform elemental concentrations. The unknown elemental concentration in each layer can be calculated using a single-angle XRF measurement, layered calibration data, and a priori knowledge of the concentration behavior as a function of depth. The method was verified using a commercial portable X-ray spectrometer and four-layer stacks of polyester resin discs doped with various concentrations of arsenic. This approach is particularly suitable for quantitative in vivo measurements of arsenic and selenium concentrations in the human skin since minimal ionizing radiation exposure constrains the number of XRF measurements. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码：1150 / 1156
页数：7
相关论文
共 21 条
123