Adherence to Antidepressant Treatment: What the Doctor Thinks and What the Patient Says

被引：8

作者：

Loayza, N. ^{[2
]}

Crettol, S. ^{[1
]}

Riquier, F. ^{[2
]}

Eap, C. B. ^{[1
,3
]}

机构：

[1] Hosp Cery, Univ Lausanne Hosp, Ctr Psychiat Neurosci, Dept Psychiat,Unit Pharmacogenet & Clin Psychopha, CH-1008 Prilly, Switzerland

[2] Hosp Cery, Univ Lausanne Hosp, Sect Karl Jaspers, Dept Psychiat, CH-1008 Prilly, Switzerland

[3] Univ Lausanne, Univ Geneva, Sch Pharmaceut Sci, Geneva, Switzerland

来源：

PHARMACOPSYCHIATRY | 2012年 / 45卷 / 05期

关键词：

patient compliance; medication adherence; antidepressive agents; MS;

D O I：

10.1055/s-0032-1306311

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Adherence to antidepressant treatment has been shown to range from 30 to 70%. The aim of this study was to compare the patient's self-report of adherence with the doctors' estimation of adherence and therapeutic alliance in 104 outpatients with mood and/or anxiety disorder treated with antidepressants. The adherence scores estimated by the patients and the doctors were significantly different, the doctors underestimating adherence in 29% of cases and overestimating it in 31% of cases compared to the patients' evaluation. Adherence measured by drug plasma concentration, despite being higher than expected from previously published reports, was in line with the patients' self-reported score but not the doctors' estimation. Finally, the patients' and the doctors' Helping Alliance scores were not related to adherence self-report.

引用

页码：204 / 207

页数：4

共 10 条

[1] TRIMIPRAMINE KINETICS AND ABSOLUTE BIOAVAILABILITY - USE OF GAS-LIQUID-CHROMATOGRAPHY WITH NITROGEN-PHOSPHORUS DETECTION [J].