Supramolecular Electrostatic Nanoassemblies for Bacterial Forensics

被引:9
作者
Duarte, Aidee [2 ]
Slutsky, Morris [3 ]
Hanrahan, Grady [1 ]
Mello, Charlene M. [3 ]
Bazan, Guillermo C. [2 ]
机构
[1] Calif Lutheran Univ, Hugh & Hazel Darling Ctr Appl Sci Comp, Dept Chem, Thousand Oaks, CA 91360 USA
[2] Univ Calif Santa Barbara, Inst Collaborat Biotechnol, Dept Chem & Biochem, Santa Barbara, CA 93106 USA
[3] US Army Natick Soldier RDEC, Biosci & Technol Team, Natick, MA 01760 USA
关键词
biosensors; forensics; fluorescent probes; FRET; microbiology; self-assembly; MEMBRANE-LIPID COMPOSITION; ESCHERICHIA-COLI O157-H7; GROWTH TEMPERATURE; BACILLUS-ANTHRACIS; GOLD-NANOPARTICLE; ADAPTATION; LIPOPOLYSACCHARIDE; IDENTIFICATION; PROTEINS; ACID;
D O I
10.1002/chem.201103237
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Electrostatic nanoassemblies were employed to identify bacterial growth conditions. They comprise a cationic conjugated oligoelectrolyte and fluorescein-tagged ssDNA and were optimized with a hybrid, computational neural network model. The photoluminescence spectra contained the oligomer and sensitized fluorescein emission. The spectra changed depending on the growth history of the bacteria introduced (see figure). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:756 / 759
页数:4
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