New bioactive glass-ceramic: Synthesis and application in PMMA bone cement composites

被引：34

作者：

Abd Samad, Hamizah ^{[1
]}

Jaafar, Mariatti ^{[1
]}

Othman, Radzali ^{[1
]}

Kawashita, Masakazu ^{[2
]}

Abdul Razak, Noor Hayati ^{[3
]}

机构：

[1] Univ Sains Malaysia, Sch Mat & Mineral Resources Engn, Nibong Tebal 14300, Penang, Malaysia

[2] Tohoku Univ, Grad Sch Biomed Engn, Sendai, Miyagi 980, Japan

[3] Univ Sains Malaysia, Sch Dent Sci, Kelantan, Malaysia

来源：

BIO-MEDICAL MATERIALS AND ENGINEERING | 2011年 / 21卷 / 04期

关键词：

Bioactive bone cement; polymethylmethacrylate; bioactivity; hydroxyapatite; glass-ceramics; MECHANICAL-PROPERTIES; STRENGTH; HA;

D O I：

10.3233/BME-2011-0673

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

In present study, a new composition of glass-ceramic was synthesized based on the Na2O-CaO-SiO2-P2O5 glass system. Heat treatment of glass powder was carried out in 2 stages: 600 degrees C as the nucleation temperature and different temperature on crystallization at 850, 950 and 1000 degrees C. The glass-ceramic heat-treated at 950 degrees C was selected as bioactive filler in commercial PMMA bone cement; (PALACOS (R) LV) due to its ability to form 2 high crystallization phases in comparison with 850 and 1000 degrees C. The results of this newly glass-ceramic filled PMMA bone cement at 0-16 wt% of filler loading were compared with those of hydroxyapatite (HA). The effect of different filler loading on the setting properties was evaluated. The peak temperature during the polymerization of bone cement decreased when the liquid to powder (L/P) ratio was reduced. The setting time, however, did not show any trend when filler loading was increased. In contrast, dough time was observed to decrease with increased filler loading. Apatite morphology was observed on the surface of the glass-ceramic and selected cement after bioactivity test.

引用

页码：247 / 258

页数：12

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