Metronidazole treatment of women with a positive fetal fibronectin test result

被引:26
|
作者
Goldenberg, RL [1 ]
Klebanoff, M
Carey, JC
MacPherson, C
机构
[1] Univ Alabama Birmingham, Birmingham, AL USA
[2] NICHHD, Bethesda, MD 20892 USA
[3] Oklahoma Univ, Oklahoma City, OK USA
[4] George Washington Univ, Ctr Biostat, Washington, DC USA
关键词
fetal fibronectin; bacterial vaginosis; preterm birth;
D O I
10.1067/mob.2001.115998
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Eighty-nine women with either bacterial vaginosis, Trichomonas vaginalis, or both, who also had a positive fetal fibronectin test result were randomized to two courses of metronidazole treatment as part of a Maternal-Fetal Medicine Network Units study of the National Institute of Child Health and Human Development. In this subgroup analysis, compared with the placebo group, women who were treated with metronidazole had a nonsignificant reduction in spontaneous preterm birth from 14.6% to 8.3%.
引用
收藏
页码:485 / 486
页数:2
相关论文
共 50 条
  • [21] The use of fetal fibronectin and cervical length measurements in the prediction of spontaneous preterm birth in women with an Arabin pessary in situ
    Martin, Anastasia
    Suff, Natalie
    Seed, Paul T.
    David, Anna L.
    Girling, Joanna
    Shennan, Andrew
    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2022, 276 : 113 - 117
  • [22] Utility of cervical length and quantitative fetal fibronectin for predicting spontaneous preterm delivery among symptomatic nulliparous women
    Kyozuka, Hyo
    Murata, Tsuyoshi
    Sato, Tetsu
    Suzuki, Satoshi
    Yamaguchi, Akiko
    Fujimori, Keiya
    INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2019, 145 (03) : 331 - 336
  • [23] Examining the relationship between positive mid-gestational fetal fibronectin assays and histological evidence of acute placental inflammation
    Akers, Aletha
    Jarzembowski, Jason A.
    Johnson, Clark T.
    Lieberman, Richard W.
    Dalton, Vanessa K.
    JOURNAL OF PERINATAL MEDICINE, 2007, 35 (01) : 36 - 42
  • [24] RETRACTED: Fetal fibronectin (Quick Check fFN test®) for detection of premature rupture of fetal membranes (Retracted Article)
    Abdelazim, Ibrahim A.
    ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2013, 287 (02) : 205 - 210
  • [25] Fetal fibronectin as a predictor of spontaneous preterm labour in asymptomatic women with a cervical cerclage
    Duhig, K. E.
    Chandiramani, M.
    Seed, P. T.
    Briley, A. L.
    Kenyon, A. P.
    Shennan, A. H.
    BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2009, 116 (06) : 799 - 803
  • [26] Cervical length and quantitative fetal fibronectin in the prediction of spontaneous preterm birth in asymptomatic women with congenital uterine anomaly
    Ridout, Alexandra E.
    Ibeto, Linda A.
    Ross, Georgia N.
    Cook, Joanna R.
    Sykes, Lynne
    David, Anna L.
    Seed, Paul T.
    Tribe, Rachel M.
    Bennett, Phillip R.
    Terzidou, Vasso
    Shennan, Andrew H.
    Chandiramani, Manju
    Brown, Richard G.
    Chatfield, Susan
    Sadeh, Dana
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2019, 221 (04) : 341.e1 - 341.e9
  • [27] Which Factors Contribute to False-Positive, False-Negative, and Invalid Results in Fetal Fibronectin Testing in Women with Symptoms of Preterm Labor?
    Bruijn, Merel M. C.
    Hermans, Frederik J. R.
    Vis, Jolande Y.
    Wilms, Femke F.
    Oudijk, Martijn A.
    Kwee, Anneke
    Porath, Martina M.
    Oei, Guid
    Scheepers, Hubertina C. J.
    Spaanderman, Marc E. A.
    Bloemenkamp, Kitty W. M.
    Haak, Monique C.
    Bolte, Antoinette C.
    Vandenbussche, Frank P. H. A.
    Woiski, Mallory D.
    Bax, Caroline J.
    Cornette, Jerome M. J.
    Duvekot, Johannes J.
    Bijvank, Bas W. A. N. I. J.
    van Eyck, Jim
    Franssen, Maureen T. M.
    Sollie, Krystyna M.
    van der Post, Joris A. M.
    Bossuyt, Patrick M. M.
    Kok, Marjolein
    Mol, Ben W. J.
    van Baaren, Gert-Jan
    AMERICAN JOURNAL OF PERINATOLOGY, 2017, 34 (03) : 234 - 239
  • [28] Evaluation of the quantitative fetal fibronectin test and PAMG-1 test for the prediction of spontaneous preterm birth in patients with signs and symptoms suggestive of preterm labor
    Ravi, Mini
    Beljorie, Mercy
    El Masry, Karim
    JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 2019, 32 (23) : 3909 - 3914
  • [29] The fetal fibronectin test is superior to cervical length measurement in predicting preterm birth in twin pregnancies: a retrospective observational study
    Holzer, Iris
    Koch-Trappel, Markus
    Leitich, Harald
    Meyer, Elias Laurin
    Farr, Alex
    Helmer, Hanns
    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2020, 247 : 22 - 25
  • [30] Rapid fetal fibronectin swab-test in preterm labor patients treated by betamimetics
    Benattar, C
    Taieb, J
    Fernandez, H
    Lindendaum, A
    Frydman, R
    Ville, Y
    EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 1997, 72 (02): : 131 - 135