Metabolic syndrome in children (Review)

被引:7
作者
Wu, Yue-E [1 ]
Zhang, Chong-Lin [1 ]
Zhen, Qing [1 ]
机构
[1] Xuzhou Childrens Hosp, Dept Respirat, 8 Sudibei Rd, Xuzhou 221002, Jiangsu, Peoples R China
关键词
metabolic syndrome; cardiometabolic risk factors; infants; FATTY LIVER-DISEASE; OBSTRUCTIVE SLEEP-APNEA; CORONARY-HEART-DISEASE; TYPE-2; DIABETES-MELLITUS; LIFE-STYLE INTERVENTION; INSULIN-RESISTANCE; CARDIOVASCULAR-DISEASE; RISK-FACTORS; ATHEROSCLEROSIS RISK; CARDIOMETABOLIC RISK;
D O I
10.3892/etm.2016.3632
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors, including central obesity, insulin resistance, glucose intolerance, dyslipidemia and increased blood pressure. The prevalence of MetS is on the increase worldwide owing to the epidemic of overweight and obesity. The risk of prevalence of MetS greatly increases during adulthood for those children exposed to cardiometabolic risk factors in their early lives. MetS has also been associated with liver fat accumulation in children. Elevated levels of plasma alanine aminotransferase and -glutamyl transferase have been associated with liver fat accumulation. The present review aimed to expand knowledge on the clustering of cardiometabolic risk factors responsible for the widespread occurrence of metabolic disease in children.
引用
收藏
页码:2390 / 2394
页数:5
相关论文
共 66 条
[1]   Relationship between obesity, insulin resistance, and coronary heart disease risk [J].
Abbasi, F ;
Brown, BW ;
Lamendola, C ;
McLaughlin, T ;
Reaven, GM .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2002, 40 (05) :937-943
[2]   Harmonizing the Metabolic Syndrome A Joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity [J].
Alberti, K. G. M. M. ;
Eckel, Robert H. ;
Grundy, Scott M. ;
Zimmet, Paul Z. ;
Cleeman, James I. ;
Donato, Karen A. ;
Fruchart, Jean-Charles ;
James, W. Philip T. ;
Loria, Catherine M. ;
Smith, Sidney C., Jr. .
CIRCULATION, 2009, 120 (16) :1640-1645
[3]  
Ash-Bernal Rachel, 2006, J Cardiometab Syndr, V1, P25, DOI 10.1111/j.0197-3118.2006.05452.x
[4]   Longitudinal changes in cardiovascular risk from childhood to young adulthood in offspring of parents with coronary artery disease - The Bogalusa Heart Study [J].
Bao, WH ;
Srinivasan, SR ;
Valdez, R ;
Greenlund, KJ ;
Wattigney, WA ;
Berenson, GS .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 278 (21) :1749-1754
[5]   The endocrinology of food intake [J].
Begg, Denovan P. ;
Woods, Stephen C. .
NATURE REVIEWS ENDOCRINOLOGY, 2013, 9 (10) :584-597
[6]   Ectopic lipid storage and insulin resistance: a harmful relationship [J].
Boren, J. ;
Taskinen, M. -R. ;
Olofsson, S. -O. ;
Levin, M. .
JOURNAL OF INTERNAL MEDICINE, 2013, 274 (01) :25-40
[7]   Non-alcoholic fatty liver disease in obese children and the relationship between metabolic syndrome criteria [J].
Boyraz, Mehmet ;
Hatipoglu, Nihal ;
Sari, Erkan ;
Akcay, Arzu ;
Taskin, Necati ;
Ulucan, Korkut ;
Akcay, Teoman .
OBESITY RESEARCH & CLINICAL PRACTICE, 2014, 8 (04) :E356-E363
[8]   Long-term outcome in children of mothers with gestational diabetes [J].
Burguet, A. .
DIABETES & METABOLISM, 2010, 36 (06) :682-694
[9]   The Metabolic Responses to L-Glutamine of Livers from Rats with Diabetes Types 1 and 2 [J].
Comar, Jurandir Fernando ;
de Oliveira, Denise Silva ;
Bracht, Livia ;
Kemmelmeier, Fumie Suzuki ;
Peralta, Rosane Marina ;
Bracht, Adelar .
PLOS ONE, 2016, 11 (08)
[10]   Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes [J].
DeFronzo, Ralph A. ;
Tripathy, Devjit .
DIABETES CARE, 2009, 32 :S157-S163