Synthesis of novel functionalized dihydroimidazo[2,1-a] isoquinolines and dihydroimidazo[2,1-a] quinolines: single crystal X-ray studies of (Z)-methyl 2-(1-(benzo[d]thiazol-2-yl)-2-oxo-1,2-dihydroimidazo [2,1-a] isoquinolin-3 (10bH)-ylidene)acetate

被引：14

作者：

Arab-Salmanabadi, Samira ^{[1
]}

Dorvar, Marzieh ^{[1
]}

Notash, Behrouz ^{[2
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Shahr E Qods Branch, Tehran, Iran

[2] Shahid Beheshti Univ, Dept Chem, GC, Tehran 1983963113, Iran

来源：

TETRAHEDRON | 2015年 / 71卷 / 08期

关键词：

Dihydroimidazo[2,1-a]isoquinoline; Dihydroimidazo[2,1-a]quinoline; Nitrogen heterocycles; Zwitterionic intermediate; Single crystal X-ray; ONE-POT SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; SATURATED HETEROCYCLES; ACTIVATED ACETYLENES; CATALYZED SYNTHESIS; EFFICIENT; OPTIMIZATION; INHIBITORS;

D O I：

10.1016/j.tet.2014.12.076

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of novel functionalized dihydroimidazo[2,1-a]isoquinolines and dihydroimidazo[2,1-a] quinolines were synthesized via the reaction between isoquinoline or quinoline derivatives and dialkyl acetylenedicarboxylates in the presence of 2-aminobenzothiazole in excellent yields. These novel synthesized compounds were suitably characterized by elemental analysis, Mass spectroscopy, IR, H-1-NMR & C-13-NMR spectra. In addition the compound (Z)-methyl 2-(1-(benzo[d]thiazol-2-yl)-2-oxo-1,2-dihydroimidazo[2,1-a]isoquinolin-3(10bH)-ylidene)acetate was subjected to the single crystal X-ray diffraction studies. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：1292 / 1296

页数：5

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