Robinlin:: A novel bioactive homo-monoterpene from Robinia pseudoacacia L. (Fabaceae)

被引：22

作者：

Tian, FF

Chang, CJ

Grutzner, JB

Nichols, DE

McLaughlin, JL

机构：

[1] Nat Sunshine Prod Inc, Spanish Fork, UT 84660 USA

[2] Purdue Univ, Sch Sci, Dept Chem, W Lafayette, IN 47907 USA

[3] Purdue Univ, Sch Sci, Sch Pharm & Pharmacal Sci, Dept Med Chem & Mol Pharmacol, W Lafayette, IN 47907 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2001年 / 11卷 / 19期

关键词：

D O I：

10.1016/S0960-894X(01)00514-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A bioactivity-directed fractionation or the ethanolic extracts of Robinia pseudoacacia L. (Fabaceae) afforded robinlin (1), a novel homo-monoterpene. The structure of 1was elucidated by spectral analyses of the parent compound as well as its derivatives: 1 showed strong bioactivity in the brine shrimp lethality test (BST). (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2603 / 2606

页数：4

共 11 条

[1]

Cooper M.R., 1984, POISONOUS PLANTS BRI, P305

[2]

FIELDER M, 1975, PLANT MED FOLKLORE, P106

[3]

FOSTER S, 1990, RT PETERSON FIELD GU, P274

[4]

GU ZM, 1993, HETEROCYCLES, V36, P2221

[5]

ISOE S, 1969, Tetrahedron Letters, V4, P279

[6]

KINGSBURG JOHN M., 1964

[7]

Mclaughlin JL, 1991, METHODS PLANT BIOCH, V6, P1

[8] HIGH-FIELD FT NMR APPLICATION OF MOSHER METHOD - THE ABSOLUTE-CONFIGURATIONS OF MARINE TERPENOIDS [J].

OHTANI, I ;

KUSUMI, T ;

KASHMAN, Y ;

KAKISAWA, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (11) :4092-4096

[9]

SHROPSHIRE CM, 1992, J AM VET MED ASSOC, V200, P936

[10]

Tian F, 2000, PHARM BIOL, V38, P229, DOI 10.1076/1388-0209(200007)3831-SFT229

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