A comparative analysis of photoinduced tumors necrosis with/without a photosensitizer

被引:0
作者
Biziuk, Siarhei A. [1 ]
Dzhagarov, Boris M. [1 ]
Istomin, Yury P. [2 ]
Parkhats, Marina V. [1 ]
机构
[1] NAS Belarus, Inst Atom & Mol Phys, Nezavisimosti Ave 70, Minsk 220072, BELARUS
[2] Minist Hlth, NN Alexandrov Res Inst Oncol & Med Radiol, Minsk 223040, BELARUS
来源
INTERNATIONAL CONFERENCE ON LASERS, APPLICATIONS, AND TECHNOLOGIES 2007: LASER TECHNOLOGIES FOR MEDICINE | 2007年 / 6734卷
关键词
photodynamic therapy of cancer; tumor necrosis; photoinduced reaction; laser irradiation; photosensitizer;
D O I
10.1117/12.753347
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The results of an irradiation of sensitized and non-sensitized tumors Pliss lymphosarcoma. are presented in the paper. The experimental data and the theoretical calculations show, that hemoglobin can be considered as a primary agent, the photoexcitation of which induces cytotoxic reactions resulting in a tumors destruction without an exogenous singlet oxygen photosensitizer. Several mechanisms of a laser action on biological tissues, which can hypothetically influence on PDT efficiency, are discussed in the paper.
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页数:7
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