Zinc perchlorate catalyzed one-pot synthesis of 3,4-dihydropyrimidinones under solvent-free conditions

被引：12
|
作者：
Palekar, Vikrant S. [1 ]
Shukla, Sanjeev R. [1 ]
机构：
[1] Univ Mumbai, Inst Chem Technol Autonomous, Mumbai, Maharashtra, India
来源：
GREEN CHEMISTRY LETTERS AND REVIEWS | 2008年 / 1卷 / 03期
关键词：
Biginelli reaction; 3,4-dihydropyrimidin-2(1H)-ones; zinc perchlorate catalyst; solvent-free condition;
D O I：
10.1080/17518250802541490
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In this paper, we report zinc perchlorate hexahydrate [Zn(ClO4)(2)center dot 6H(2)O] as a highly effective catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones under solvent-free conditions. These improved reaction conditions allow the preparation of a wide variety of substituted dihydropyrimidinones in high yields and purity under mild reaction conditions. Compared with the classical Biginelli reaction, this method has the advantage of excellent yields and short reaction time in solvent-free conditions.
引用
收藏
页码：185 / 190
页数：6
相关论文
共 50 条
  • [41] HOTf-catalyzed sustainable one-pot synthesis of benzene and pyridine derivatives under solvent-free conditions
    Zhang, Xu
    Wang, Zhiqiang
    Xu, Kun
    Feng, Yuquan
    Zhao, Wei
    Xu, Xuefeng
    Yan, Yanlei
    Yi, Wei
    GREEN CHEMISTRY, 2016, 18 (08) : 2313 - 2316
  • [42] Molybdate sulfuric acid-catalyzed one-pot synthesis of substituted coumarins under solvent-free conditions
    Saeed Khodabakhshi
    Bahador Karami
    Khalil Eskandari
    Research on Chemical Intermediates, 2015, 41 : 7263 - 7272
  • [43] [Zn(L-proline)2] Catalyzed One-Pot Synthesis of Propargylamines Under Solvent-Free Conditions
    Layek, Samaresh
    Agrahari, Bhumika
    Kumari, Shweta
    Anuradha
    Pathak, Devendra D.
    CATALYSIS LETTERS, 2018, 148 (09) : 2675 - 2682
  • [44] Iodine-catalyzed three-component one-pot synthesis of naphthopyranopyrimidines under solvent-free conditions
    Kumar, K. Praveen
    Satyanarayana, S.
    Reddy, P. Lakshmi
    Narasimhulu, G.
    Ravirala, Narender
    Reddy, B. V. Subba
    TETRAHEDRON LETTERS, 2012, 53 (14) : 1738 - 1741
  • [45] Molybdate sulfuric acid-catalyzed one-pot synthesis of substituted coumarins under solvent-free conditions
    Khodabakhshi, Saeed
    Karami, Bahador
    Eskandari, Khalil
    RESEARCH ON CHEMICAL INTERMEDIATES, 2015, 41 (10) : 7263 - 7272
  • [46] Strontium chloride-catalyzed one-pot synthesis of 4(3H)-quinazolinones under solvent-free conditions
    Min Wang~(a
    ChineseChemicalLetters, 2010, 21 (10) : 1167 - 1170
  • [47] AMMONIUM CHLORIDE-CATALYZED ONE-POT SYNTHESIS OF 4(3H)-QUINAZOLINONES UNDER SOLVENT-FREE CONDITIONS
    Huang, Guoli
    Liu, Bo
    Teng, Mingyu
    Chen, Yegao
    SYNTHETIC COMMUNICATIONS, 2014, 44 (12) : 1786 - 1794
  • [48] Strontium chloride-catalyzed one-pot synthesis of 4(3H)-quinazolinones under solvent-free conditions
    Wang, Min
    Song, Zhi Guo
    Zhang, Ting Ting
    CHINESE CHEMICAL LETTERS, 2010, 21 (10) : 1167 - 1170
  • [49] One-Pot synthesis of dihydropyrimidinones by dodecylphosphonic acid as solid Bronsted Acid Catalyst under Solvent-Free Conditions via Biginelli condensation
    S. Ghassamipour
    A. R. Sardarian
    Journal of the Iranian Chemical Society, 2010, 7 : 237 - 242
  • [50] One-Pot Synthesis of Dihydropyrimidinones by Dodecylphosphonic Acid as Solid Bronsted Acid Catalyst under Solvent-Free Conditions via Biginelli Condensation
    Ghassamipour, S.
    Sardarian, A. R.
    JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2010, 7 (01) : 237 - 242
12345