Food Insecurity, HIV Disease Progression and Access to Care Among HIV-Infected Russians not on ART

被引：5

作者：

Idrisov, Bulat ^{[1
]}

Lunze, Karsten ^{[1
]}

Cheng, Debbie M. ^{[2
]}

Blokhina, Elena ^{[3
]}

Gnatienko, Natalia ^{[4
]}

Patts, Gregory J. ^{[5
]}

Bridden, Carly ^{[4
]}

Kleinman, Ronald E. ^{[6
]}

Weiser, Sheri D. ^{[7
]}

Krupitsky, Evgeny ^{[8
]}

Samet, Jeffrey H. ^{[1
,9
]}

机构：

[1] Boston Univ, Gen Internal Med Sect, Dept Med, Clin Addict Res & Educ Unit,Sch Med,Boston Med Ct, 801 Massachusetts Ave,2nd Floor, Boston, MA 02118 USA

[2] Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA

[3] First Pavlov State Med Univ, Lab Clin Pharmacol Addict, St Petersburg, Russia

[4] Boston Med Ctr, Gen Internal Med Sect, Dept Med, Clin Addict Res & Educ Unit, Boston, MA USA

[5] Boston Univ, Sch Publ Hlth, Data Coordinating Ctr, Boston, MA USA

[6] Massachusetts Gen Hosp, Dept Pediat, Boston, MA 02114 USA

[7] UCSF, Div HIV Infect Dis & Global Med, Dept Med, San Francisco, CA USA

[8] Bekhterev Res Psychoneurol Inst, Dept Addict, St Petersburg, Russia

[9] Boston Univ, Sch Publ Hlth, Dept Community Hlth Sci, Boston, MA 02215 USA

来源：

AIDS AND BEHAVIOR | 2017年 / 21卷 / 12期

关键词：

HIV progression; Russia; Food insecurity; Access to care; CRACK-COCAINE USERS; MEDICATION ADHERENCE; ANTIRETROVIRAL THERAPY; RNA SUPPRESSION; DRUG-USERS; PEOPLE; HEALTH; INSUFFICIENCY; HIV/AIDS; INDIVIDUALS;

D O I：

10.1007/s10461-017-1885-4

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Food insecurity (FI) has been associated with HIV disease progression among people on antiretroviral therapy (ART), presumably a consequence of poor medication adherence. We assessed whether there is a longitudinal association between FI and two primary outcomes reflecting on HIV disease progression (i.e., CD4 count and time to ART initiation) among people not on ART. Analyses used linear mixed effects and Cox models controlling for confounders. In this cohort (n = 310) FI was common (53%). Most (71.3%) reported past month heavy alcohol use and 37.1% reported past month injection drug use. Only 50 participants initiated ART during the study and mean time to ART was 128 days (SD 120). There were no significant differences in CD4 cell count between the groups with mild/moderate FI or severe FI versus those with no FI [adjusted mean difference, mild/moderate insecurity versus no FI -32.5 (95% CI -94.3, 29.3); severe versus no FI -45.5 (95% CI -124.1, 33.0); global p = 0.42]. We found no significant association between FI and longer time to ART initiation (p = 0.36). Food security is a desirable goal for overall health and shown beneficial for those on ART, however it does not appear to be associated with HIV disease progression among those with high prevalence of substance use and not yet on ART.

引用

页码：3486 / 3495

页数：10