Outpatient Parenteral Antimicrobial Therapy Plus Buprenorphine for Opioid Use Disorder and Severe Injection-related Infections

被引：60

作者：

Fanucchi, Laura C. ^{[1
]}

Walsh, Sharon L. ^{[2
]}

Thornton, Alice C. ^{[3
]}

Nuzzo, Paul A. ^{[2
]}

Lofwall, Michelle R. ^{[2
]}

机构：

[1] Univ Kentucky, Div Infect Dis, Ctr Drug & Alcohol Res, 845 Angliana Ave, Lexington, KY 40508 USA

[2] Univ Kentucky, Ctr Drug & Alcohol Res, Lexington, KY 40508 USA

[3] Univ Kentucky, Div Infect Dis, Lexington, KY 40508 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2020年 / 70卷 / 06期

基金：

美国国家卫生研究院;

关键词：

endocarditis; opioid-related disorders; buprenorphine; injection-drug use; antibiotics; SUBSTANCE USE;

D O I：

10.1093/cid/ciz654

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-related infections, an innovative care model combining outpatient parenteral antimicrobial therapy with buprenorphine treatment had similar clinical and drug use outcomes to usual care (inpatient intravenous antibiotic completion) and shortened hospital length of stay by 23.5 days.

引用

页码：1226 / 1229

页数：4

共 14 条

[1]

American Psychiatric Association, 1980, Diagnostic and Statistical Manual of Mental Disorders, V3rd ed.

[2] A 9-Point Risk Assessment for Patients Who Inject Drugs and Require Intravenous Antibiotics: Focusing Inpatient Resources on Patients at Greatest Risk of Ongoing Drug Use [J].

Eaton, Ellen F. ;

Mathews, Ronnie E. ;

Lane, Peter S. ;

Paddock, Cayce S. ;

Rodriguez, Jorge Martin ;

Taylor, Benjamin B. ;

Saag, Michael S. ;

Kilgore, Meredith L. ;

Lee, Rachael A. .

CLINICAL INFECTIOUS DISEASES, 2019, 68 (06) :1041-1043

[3]

Fanucchi L, 2019, INTEGRATED OUTPATIEN

[4] In-hospital illicit drug use, substance use disorders, and acceptance of residential treatment in a prospective pilot needs assessment of hospitalized adults with severe infections from injecting drugs [J].

Fanucchi, Laura C. ;

Lofwall, Michelle R. ;

Nuzzo, Paul A. ;

Walsh, Sharon L. .

JOURNAL OF SUBSTANCE ABUSE TREATMENT, 2018, 92 :64-69

[5] Hospitalizations for Endocarditis and Associated Health Care Costs Among Persons with Diagnosed Drug Dependence - North Carolina, 2010-2015 [J].

Fleischauer, Aaron T. ;

Ruhl, Laura ;

Rhea, Sarah ;

Barnes, Erin .

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2017, 66 (22) :569-573

[6] Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis [J].

Iversen, Kasper ;

Ihlemann, Nikolaj ;

Gill, Sabine U. ;

Madsen, Trine ;

Elming, Hanne ;

Jensen, Kaare T. ;

Bruun, Niels E. ;

Hofsten, Dan E. ;

Fursted, Kurt ;

Christensen, Jens J. ;

Schultz, Martin ;

Klein, Christine F. ;

Fosboll, Emil L. ;

Rosenvinge, Flemming ;

Schonheyder, Henrik C. ;

Kober, Lars ;

Torp-Pedersen, Christian ;

Helweg-Larsen, Jannik ;

Tonder, Niels ;

Moser, Claus ;

Bundgaard, Henning .

NEW ENGLAND JOURNAL OF MEDICINE, 2019, 380 (05) :415-424

[7]

Jackson KA, 2018, MMWR-MORBID MORTAL W, V67, P625, DOI 10.15585/mmwr.mm6722a2

[8] Oral versus Intravenous Antibiotics for Bone and Joint Infection [J].

Li, H. -K. ;

Rombach, I. ;

Zambellas, R. ;

Walker, A. S. ;

McNally, M. A. ;

Atkins, B. L. ;

Lipsky, B. A. ;

Hughes, H. C. ;

Bose, D. ;

Kumin, M. ;

Scarborough, C. ;

Matthews, P. C. ;

Brent, A. J. ;

Lomas, J. ;

Gundle, R. ;

Rogers, M. ;

Taylor, A. ;

Angus, B. ;

Byren, I. ;

Berendt, A. R. ;

Warren, S. ;

Fitzgerald, F. E. ;

Mack, D. J. F. ;

Hopkins, S. ;

Folb, J. ;

Reynolds, H. E. ;

Moore, E. ;

Marshall, J. ;

Jenkins, N. ;

Moran, C. E. ;

Woodhouse, A. F. ;

Stafford, S. ;

Seaton, R. A. ;

Vallance, C. ;

Hemsley, C. J. ;

Bisnauthsing, K. ;

Sandoe, J. A. T. ;

Aggarwal, I. ;

Ellis, S. C. ;

Bunn, D. J. ;

Sutherland, R. K. ;

Barlow, G. ;

Cooper, C. ;

Geue, C. ;

McMeekin, N. ;

Briggs, A. H. ;

Sendi, P. ;

Khatamzas, E. ;

Wangrangsimakul, T. ;

Wong, T. H. N. .

NEW ENGLAND JOURNAL OF MEDICINE, 2019, 380 (05) :425-436

[9] Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis [J].

Li, JS ;

Sexton, DJ ;

Mick, N ;

Nettles, R ;

Fowler, VG ;

Ryan, T ;

Bashore, T ;

Corey, GR .

CLINICAL INFECTIOUS DISEASES, 2000, 30 (04) :633-638

[10] THE 5TH EDITION OF THE ADDICTION SEVERITY INDEX [J].

MCLELLAN, AT ;

KUSHNER, H ;

METZGER, D ;

PETERS, R ;

SMITH, I ;

GRISSOM, G ;

PETTINATI, H ;

ARGERIOU, M .

JOURNAL OF SUBSTANCE ABUSE TREATMENT, 1992, 9 (03) :199-213

← 1 2 →