Hydrophobicity of surface-immobilised molecules influences architectures formed via interfacial self-assembly of nucleoside-based gelators

被引:7
作者
Angelerou, Maria Galini Faidra [1 ]
Yang, Bin [1 ]
Arnold, Thomas [2 ,3 ,4 ,5 ]
Rawle, Jonathan [2 ]
Marlow, Maria [1 ]
Zelzer, Mischa [1 ]
机构
[1] Univ Nottingham, Dept Pharm, Nottingham NG2 7RD, England
[2] Diamond Light Source Ltd, Harwell Sci & Innovat Campus, Didcot OX11 0DE, Oxon, England
[3] European Spallat Source ERIC, POB 176, SE-22100 Lund, Sweden
[4] STFC, Rutherford Appleton Lab, Didcot OX11 0QX, Oxon, England
[5] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England
基金
英国工程与自然科学研究理事会;
关键词
SUPRAMOLECULAR GELS; PEPTIDE AMPHIPHILES; DRUG-DELIVERY;
D O I
10.1039/c8sm01868e
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Surface-mediated self-assembly has potential in biomaterial development but underlying rules governing surface-gelator interactions are poorly understood. Here, we correlate surface properties with structural characterization data of nucleoside-based gels obtained by GISAXS and GIWAXS and find that hydrophobicity descriptors (logP, polar surface area, aromaticity) are key predictors for the gel structures formed.
引用
收藏
页码:9851 / 9855
页数:5
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