Residues of pharmaceutical products in recycled organic manure produced from sewage sludge and solid waste from livestock and relationship to their fermentation level

被引：68

作者：

Motoyama, Miki ^{[1
]}

Nakagawa, Shuhei ^{[2
]}

Tanoue, Rumi ^{[1
]}

Sato, Yuri ^{[1
]}

Nomiyama, Kei ^{[3
]}

Shinohara, Ryota ^{[1
]}

机构：

[1] Prefectural Univ Kumamoto, Grad Sch Environm & Symbiot Sci, Kumamoto 8628502, Japan

[2] Nodaichidenshi Corp Ltd, Kumamoto 8600823, Japan

[3] Ehime Univ, CMES, Matsuyama, Ehime 7908577, Japan

来源：

CHEMOSPHERE | 2011年 / 84卷 / 04期

基金：

日本学术振兴会;

关键词：

Pharmaceutical products; Human waste sludge; Sewage sludge; Solid waste from livestock; Recycled organic manure; Fermentation; PERSONAL CARE PRODUCTS; VETERINARY ANTIBIOTICS; TREATMENT PLANTS; WATER TREATMENT; ANAEROBIC-DIGESTION; ANIMAL MANURE; SULFONAMIDES; FATE; TRIMETHOPRIM; ENVIRONMENT;

D O I：

10.1016/j.chemosphere.2011.03.048

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

In recent years, sludge generated in sewage treatment plants (STPs) and solid waste from livestock being utilized is useful for circulation of nourishment in farmlands as recycled organic manure (ROM). In this study, we determined the residue levels and patterns of 12 pharmaceutical products generated by human activity in the ROMs produced from human waste sludge (HWS), sewage sludge (SS), cattle manure (CM), poultry manure (PM), swine manure (SM) and horse manure (HM). The kind and number of pharmaceutical products detected in ROMs were different. Fluoroquinolones (FQs) were detected at high levels in HWS and SS samples. In addition, the detection frequency and concentration levels of sulfonamides (SAs) in PM and SM were high. Moreover, high concentrations of chlortetracycline (CTC) were found in only SM. These differences reflect specific adherence adsorption of the pharmaceutical products to different livestock and humans. Moreover, it was found that the concentrations of pharmaceutical products and fermentation levels of ROMs had significant positive correlation (r = 0.41, p = 0.024). When the fermentation test of ROM was conducted in a rotary fermentor in a lab scale test, the residue levels of pharmaceutical products decreased effectively except carbamazepine (CBZ). The rates of decrease were in the case of tetracyclines (TCs): 85-92%, FQs: 81-100%, erythromycine: 67%, SAs: 79-95%, trimethoprim: 86% and CBZ: 37% by 30 d. Pharmaceutical products that can be decomposed by fermentation process at the lowest impact of residual antibiotic activities may therefore be considered as environmentally friendly medicines. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：432 / 438

页数：7

共 29 条

[1] Composting rapidly reduces levels of extractable oxytetracycline in manure from therapeutically treated beef calves [J].

Arikan, Osman A. ;

Sikora, Lawrence J. ;

Mulbry, Walter ;

Khan, Shahamat U. ;

Foster, Gregory D. .

BIORESOURCE TECHNOLOGY, 2007, 98 (01) :169-176

[2] Antimicrobial residues in animal waste and water resources proximal to large-scale swine and poultry feeding operations [J].

Campagnolo, ER ;

Johnson, KR ;

Karpati, A ;

Rubin, CS ;

Kolpin, DW ;

Meyer, MT ;

Esteban, JE ;

Currier, RW ;

Smith, K ;

Thu, KM ;

McGeehin, M .

SCIENCE OF THE TOTAL ENVIRONMENT, 2002, 299 (1-3) :89-95

[3] Carbamazepine as a possible anthropogenic marker in the aquatic environment: investigations on the behaviour of Carbamazepine in wastewater treatment and during groundwater infiltration [J].

Clara, M ;

Strenn, B ;

Kreuzinger, N .

WATER RESEARCH, 2004, 38 (04) :947-954

[4] Fate of sulfonamides, macrolides, and trimethoprim in different wastewater treatment technologies [J].

Goebel, Anke ;

McArdell, Christa S. ;

Joss, Adriano ;

Siegrist, Hansruedi ;

Giger, Walter .

SCIENCE OF THE TOTAL ENVIRONMENT, 2007, 372 (2-3) :361-371

[5] Determination of Thirteen Antibiotics Residues in Manure by Solid Phase Extraction and High Performance Liquid Chromatography [J].

Hu Xian-Gang ;

Luo Yi ;

Zhou Qi-Xing ;

Xu Lin .

CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2008, 36 (09) :1162-1166

[6]

Jongbloed AW, 1998, J ANIM SCI, V76, P2641

[7] The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK [J].

Kasprzyk-Hordern, Barbara ;

Dinsdale, Richard M. ;

Guwy, Alan J. .

WATER RESEARCH, 2008, 42 (13) :3498-3518

[8] Veterinary antibiotics in the aquatic and terrestrial environment [J].

Kemper, Nicole .

ECOLOGICAL INDICATORS, 2008, 8 (01) :1-13

[9] Removal of antibiotics in wastewater: Effect of hydraulic and solid retention times on the fate of tetracycline in the activated sludge process [J].

Kim, S ;

Eichhorn, P ;

Jensen, JN ;

Weber, AS ;

Aga, DS .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2005, 39 (15) :5816-5823

[10] Pharmaceuticals, hormones, and other organic wastewater contaminants in US streams, 1999-2000: A national reconnaissance [J].

Kolpin, DW ;

Furlong, ET ;

Meyer, MT ;

Thurman, EM ;

Zaugg, SD ;

Barber, LB ;

Buxton, HT .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2002, 36 (06) :1202-1211

← 1 2 3 →